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Öğe Acute kidney injury in an adolescent: Answers(Springer, 2021) Nalcacıoğlu, Hülya; Tekcan, Demet; Can Meydan, Bilge; Özkaya, OzanFirst, we excluded the chronic state of this patient by looking at his previous creatinine value and experienced an acute rise in the plasma creatinine so defined as acute kidney injury (AKI)Öğe Acute kidney injury in an adolescent: Questions(Springer, 2021) Nalcacıoğlu, Hülya; Tekcan, Demet; Can Meydan, Bilge; Özkaya, OzanA 17-year-old male was admitted to a local hospital with complaints of vomiting, abdominal pain, and loose watery non bloody stools per 3 days. At the same time, he noticed a decrease in his urine output over the last 2 days. His past medical history was unremarkable. There was no history of ingesting undercooked meat, fever, ill contact, or taking any medication. He was the son of healthy non-consanguineous parents. On admission, hypotension and tachycardia was noted and physical examination was unremarkable. He had received intravenous fluid replacement for 2 days at this local hospital. Due to decrease in urine output and deterioration of his renal function (serum creatinine 4.6 mg/dl) with acidosis (pH 7.2, HCO3 10 mEq/l), the patient was transferred to our centerÖğe Assessment of bioelectrical impedance analysis for determining dry weight in pediatric hemodialysis patients; single center experience(2018) Nalcacıoğlu, Hülya; Özkaya, OzanAim: Maintaining euvolemia is an important purpose in patients on hemodialysis therapy. Multiple-frequency bioimpedance spectroscopy (BIS) appears to be a useful and appropriate technique for assessing hydration status and body composition in hemodialysis patients.The aims of this study were to determine the pre and post hemodialysis hydration status of the pediatric hemodialysis patients by BIS and compare the dry weight determined by BIS to established by clinically. Material and Methods: Body Composition Monitor (BCM; Fresenius Medical Care, Germany) was performed in 13 pediatric hemodialysis patients in a single center. Patients were measured at the midweek session, once immediately before and once 30 minutes after dialysis. Pre-and post-HD weights, blood pressures, were collected on the day of the BCM measurements. Results: Seven (53.8%) of the 13 patients were male and 6 (46.2%) were female. The mean age ranged from 11.92 ± 3.13 (5.7-16) years and duration time ranged from 7 to 54 months, and the median duration of dialysis was 11 months. Dry weights which was determined clinically were higher than those calculated by BCM. A significant difference was found between mean values (34,71 ± 12,68 versus 33,71 ± 12,16 kg, ?: 1 ± 1,51, p = 0.035). There was a high positive correlation between dry weights measured by BCM and dry weight established by nephrologists (r = 0.993, p <0.001). Conclusion: In assessing dry weight, BCM appears to be a quick and easy-to-use tool that can assist the clinician in hemodialysis treatment and optimizing patient outcomesÖğe A case of bartonellosis mimicking systemic lupus erythematosus(SAGE PUBLICATIONS LTD, 2022) Kara, Emine Manolya; Özdemir, Gül Nihal; Taşdemir, Mehmet; Ata, Serap; Karini, Belma; Valiyev, Eldar; Tutkun, İlknur Tuğal; Köse, Gülşen; Özkaya, OzanBackground and aim: Cat-scratch disease (CSD) is a systemic bacterial infection caused by Bartonella henselae. The disease is typically characterized by regional lymphadenopathy developing after scratches from domestic or feral cats. Rarely, systemic involvement may be observed. The co-occurrence with glomerulonephritis and positive antinuclear antibody (ANA) tests have been reported before. In these cases, the disease can be misdiagnosed as systemic lupus erythematosus. Ocular involvement occurs in 5%-10% of the cases with CSD, and neuroretinitis is among the common manifestations. Administration of corticosteroids (CSs) in addition to antibiotics has been shown to improve prognosis in neuroretinitis cases. However, the optimal dose and duration, remain ill-defined. Case report: In this article, we present an 11-year-old girl with CSD and neuroretinitis with a positive ANA test and hematuria, who benefited from high-dose methyl-prednisolone and antibiotics. Conclusion: Further research is warranted in order to determine the dose and duration of CSs in the treatment of Bartonella neuroretinitis.Öğe Correction to: diagnostic utility of a targeted next-generation sequencing gene panel in the clinical suspicion of systemic autoinflammatory diseases: a multi-center study (vol 39, pg 911, 2019)(Springer Heidelberg, 2019) Karacan, İlker; Balamir, Ayşe; Uğurlu, Serdal; Aydın, Aslı Kireçtepe; Everest, Elif; Zor, Seyit; Önen, Merve Özkılınç; Daşdemir, Selçuk; Özkaya, Ozan; Sözeri, Betül; Tufan, Abdurrahman; Ömeroğlu, Rukiye Eker; Öztürk, Kübra; Çakan, Mustafa; Söylemezoğlu, Oğuz; Şahin, Sezgin; Barut, Kenan; Adrovic, Amra; Seyahi, Emire; Özdoğan, Huri; Kasapcopur, Özgür; Turanlı, Eda TahirSystemic autoinflammatory diseases (sAIDs) are a heterogeneous group of disorders, having monogenic inherited forms with overlapping clinical manifestations. More than half of patients do not carry any pathogenic variant in formerly associated disease genes. Here, we report a cross-sectional study on targeted Next-Generation Sequencing (NGS) screening in patients with suspected sAIDs to determine the diagnostic utility of genetic screening. Fifteen autoinflammation/immune-related genes (ADA2-CARD14-IL10RA-LPIN2-MEFV-MVK-NLRC4-NLRP12-NLRP3-NOD2-PLCG2-PSTPIP1-SLC29A3-TMEM173- TNFRSF1A) were used to screen 196 subjects from adult/pediatric clinics, each with an initial clinical suspicion of one or more sAID diagnosis with the exclusion of typical familial Mediterranean fever (FMF) patients. Following the genetic screening, 140 patients (71.4%) were clinically followed-up and re-evaluated. Fifty rare variants in 41 patients (20.9%) were classified as pathogenic or likely pathogenic and 32 of those variants were located on the MEFV gene. We detected pathogenic or likely pathogenic variants compatible with the final diagnoses and inheritance patterns in 14/140 (10%) of patients for the following sAIDs: familial Mediterranean fever (n=7), deficiency of adenosine deaminase 2 (n=2), mevalonate kinase deficiency (n=2), Muckle–Wells syndrome (n=1), Majeed syndrome (n=1), and STING-associated vasculopathy with onset in infancy (n=1). Targeted NGS panels have impact on diagnosing rare monogenic sAIDs for a group of patients. We suggest that MEFV gene screening should be first-tier genetic testing especially in regions with high carrier rates. Clinical utility of multi-gene testing in sAIDs was as low as expected, but extensive genome-wide familial analyses in combination with exome screening would enlighten additional genetic factors causing disease.Öğe Diagnostic utility of a targeted next-generation sequencing gene panel in the clinical suspicion of systemic autoinflammatory diseases: a multi-center study(Springer Heidelberg, 2019) Karacan, İlker; Balamir, Ayşe; Uğurlu, Serdal; Aydın, Aslı Kireçtepe; Everest, Elif; Zor, Seyit; Önen, Merve Özkılınç; Daşdemir, Selçuk; Özkaya, Ozan; Sözeri, Betül; Tufan, Abdurrahman; Yıldırım, Deniz Gezgin; Yüksel, Selçuk; Ayaz, Nuray Aktay; Ömeroğlu, Rukiye Eker; Öztürk, Kübra; Çakan, Mustafa; Söylemezoğlu, Oğuz; Şahin, Sezgin; Barut, Kenan; Adrovic, Amra; Seyahi, Emire; Özdogan, Huri; Kasapçopur, Özgür; Turanlı, Eda TahirSystemic autoinflammatory diseases (sAIDs) are a heterogeneous group of disorders, having monogenic inherited forms with overlapping clinical manifestations. More than half of patients do not carry any pathogenic variant in formerly associated disease genes. Here, we report a cross-sectional study on targeted Next-Generation Sequencing (NGS) screening in patients with suspected sAIDs to determine the diagnostic utility of genetic screening. Fifteen autoinflammation/immune-related genes (ADA2-CARD14-IL10RA-LPIN2-MEFV-MVK-NLRC4-NLRP12-NLRP3-NOD2-PLCG2-PSTPIP1-SLC29A3-TMEM173-TNFRSF1A) were used to screen 196 subjects from adult/pediatric clinics, each with an initial clinical suspicion of one or more sAID diagnosis with the exclusion of typical familial Mediterranean fever (FMF) patients. Following the genetic screening, 140 patients (71.4%) were clinically followed-up and re-evaluated. Fifty rare variants in 41 patients (20.9%) were classified as pathogenic or likely pathogenic and 32 of those variants were located on the MEFV gene. We detected pathogenic or likely pathogenic variants compatible with the final diagnoses and inheritance patterns in 14/140 (10%) of patients for the following sAIDs: familial Mediterranean fever (n=7), deficiency of adenosine deaminase 2 (n=2), mevalonate kinase deficiency (n=2), Muckle-Wells syndrome (n=1), Majeed syndrome (n=1), and STING-associated vasculopathy with onset in infancy (n=1). Targeted NGS panels have impact on diagnosing rare monogenic sAIDs for a group of patients. We suggest that MEFV gene screening should be first-tier genetic testing especially in regions with high carrier rates. Clinical utility of multi-gene testing in sAIDs was as low as expected, but extensive genome-wide familial analyses in combination with exome screening would enlighten additional genetic factors causing disease.Öğe Disseminated fungal infection by Aureobasidium pullulans in a renal transplant recipient(Wiley, 2018) Nalcacıoğlu, Hülya; Yakupoğlu, Y. Kamil; Genç, Gürkan; Belet, Nursen; Şensoy, Sema Gülnar; Birinci, Asuman; Özkaya, OzanRenal transplant recipients are on long-term potent immunosuppressive therapy, which makes them highly vulnerable to opportunistic fungal infections. Dematiaceous, or dark-pigmented saprophytic fungi, are being increasingly seen as opportunistic pathogens of mycoses in immunosuppressed patients. One of these is Aureobasidium pullulans, which is a black yeast-like dematiaceous fungus found ubiquitously in the environment that can cause various opportunistic human infections. Most infections occur by traumatic inoculation, such as keratitis and cutaneous lesions; disseminated mycoses are very rare and occur only in severely immunocompromised patients. We report a case of disseminated fungal infection due to A.pullulans in a pediatric patient who underwent renal transplant. The use of voriconazole and vacuum-assisted closure along with surgical drainage most likely contributed to the patient's positive outcome.Öğe The effects of joint hypermobility on quality of life in healthy school children(TR- Dizin, 2022) Saygılı, Ayşe; Saygılı, Mehmet Selçuk; Develi, Bekir Yiğit; Özkaya, OzanObjective: This study aimed to determine the prevalence of joint hypermobility in healthy primary school children and to investigate the quality of life differences between children with and without joint hypermobility. Methods: Joint hypermobility was investigated in healthy children aged 8-12 years. The “Beighton” score was evaluated for the diagnosis of joint hypermobility. According to these scores, children were divided into three groups as “joint hypermobility,” “increased joint mobility” and “no joint hypermobility.” All children were evaluated by the Pediatric Quality of Life Inventory (PedsQL) version 4 and quality of life scores were measured. The PedsQL results were compared between the groups in terms of statistical significance. Results: The mean Beighton score of 378 students enrolled in the study was 2.4±2.2. The PedsQL mean total score was 77±13.3. Age, sex distribution, pediatric PedsQL total score, psychosocial score and physical health score did not differ significantly between groups. Conclusion: Our results show that joint hypermobility does not affect the quality of life in healthy children but more extensive studies in this field are needed.Öğe The evaluation of left ventricular functions in children with steroid-sensitive nephrotic syndrome(Springer, 2018) Nalcacıoğlu, Hülya; Özkaya, Ozan; Kafalı, Candaş; Tekcan, Demet; Baysal, Kemal: Nephrotic syndrome has been associated with increased risk of cardiovascular diseases (CVD), which may be attributable to the hypoalbuminemia, dyslipidemia, hypercoagulopathy or inflammatory activation. In childhood minimal change disease is less prone to CVD because of the transient nature of the metabolic abnormalities and steroid exposure. The aim of the present study was to evaluate the presence of cardiac systolic and diastolic dysfunction in pediatric patients with steroid – sensitive nephrotic syndrome (SSNS).Öğe Evaluation of the quality of life of patients followed up with diagnosis of type 1 diabetes mellitus(Galenos Yayincilik, 2018) Duras, Ensar; Bezen, Diğdem; Özkaya, Ozan; Dursun, HasanINTRODUCTION: Quality of life level is very important in chronic diseases. We aimed to determine the quality of life level in children and adolescents diagnosed with type 1 diabetes mellitus and to conduct a comparative study with healthy peers. We also evaluated the relationship between the results and socio-demographic characteristics of the children and their families. METHODS: Forty-five children aged between 4-16 who were followed-up with the diagnosis of type 1 diabetes mellitus and a control group of 45 healthy children who were referred to the general pediatrics outpatient clinic with the similar demographic characteristics were included in the study. Sociodemographic form and the Quality of Life for Children Scale (KINDL) had been applied to all children. We also recorded the background data like diagnosis, age or any additional diseases. RESULTS: The total quality of life score was found to be 73,9 +/- 9,1 in children with type 1 diabetes mellitus, and 81,7 +/- 10,2 in the control group. Comparing the subscales of the quality of life scale, the emotional well - being, self - esteem, friend and school subscale scores of 8-12 year-old children with type 1 diabetes mellitus were statistically significantly lower than healthy group (p=0,032, p=0,041, p=0,047, p=0,029, respectively). On the other hand, there was a statistically significant difference with the scores of friend subscale in children at the age of 13-16 (p=0,043). DISCUSSION AND CONCLUSION: The quality of life of children with type 1 diabetes mellitus was significantly lower than that of the healthy children. We believe that psychosocial support from the time of diagnosis is needed for these children to improve the level of quality of life.Öğe Evaluation of the risk factors for BK virus-associated hemorrhagic cystitis in pediatric bone marrow transplantation patients: Does post-transplantation cyclophosphamide increase the frequency?(Wiley, 2022) Zengin Ersoy, Gizem; Bozkurt, Ceyhun; Adaklı Aksoy, Başak; Başoğlu Öner, Özlem; Aydoğdu, Selime; Çipe, Funda; Sütçü, Murat; Özkaya, Ozan; Tunç, FışgınBackground: BKV-HC is one of the most significant complications of HSCT. This ret -rospective study aimed to determine the frequency of BKV-HC in pediatric patients undergoing HSCT, detect the associated risk factors for the development of BKV-HC, and explore the effects of post-transplantation Cy use.Methods: Three hundred twenty-seven patients (girls: 121, boys: 206) were analyzed according to sex, conditioning regimen, transplantation type, donor relatedness, stem cell source, the presence and grade of aGVHD, CMV co-existence, and Cy use.Results: Multivariate analysis confirmed the prognostic importance of age (OR: 4.865), TBI use, the presence of aGVHD (OR: 2.794), CMV coinfection (OR: 2.261), and Cy use (OR: 27.353). A statistically significant difference was found between the mean BKV-HC follow-up times compared with post-transplantation Cy intake (p< .001). The BKV-HC rate increased as the number of risk factors of the patient increased.Conclusion: BKV-HC is an essential complication of HSCT primarily associated with Cy use, the presence of aGVHD, and donor relatedness. The present study shows that the use of Cy in the post-transplantation period further increases BKV-HC risk in pediatric patients, regardless of dose.Öğe Kidney transplantation in children weighing 15 kilograms or less(SPRINGER, 2021) Özkaya, Ozan; Evrengül, Havva; Eren, Eryiğit; Tokaç, Mehmet; Yaman, Ayhan; Şahin, Taylan; Sütçü, Murat; Dursun, İsmail; Dinçkan, Ayhan[No Abstract Available]Öğe Nephrotic syndrome following hepatitis B vaccination: A 17-year follow-up(2021) Yılmaz, Buğra; Özkaya, Ozan; İşlek, İsmailABSTRACT Some case reports described nephrotic syndrome (NS) associated with administering various vaccines in two last decades. They report only 1 year follow-up. We want to summarize the 17-year clinical follow-up of the patient who had been reported in 2000 because of developing NS after hepatitis B vaccination. Our patient first suffered from NS following hepatitis B vaccination in 4 years old. He had been treated with standard prednisolone regimen resulting in complete remission. After the first diagnosis, he had three relapses in following years. Each relapse developed after Salk, pneumococcal, and flu vaccines, respectively. Relapses had been easily controlled by prednisolone. He had seven relapses until 14 years of age. Fortunately, no relapse has been observed between 2009 and 2016. Although he has been taking alendronate and Vitamin-D for osteoporosis, he is a healthy young adult now. We think that some vaccines may induce relapses in NS, as a triggering factor without being the primarily responsible factors.Öğe Nutcracker syndrome in children: role of doppler ultrasonographic indices in detecting the pattern of symptoms(Mdpi, 2018) Nalçacıoğlu, Hülya; Bilgici, Meltem Ceyhan; Tekcan, Demet; Genç, Gürkan; Bostancı, Yakup; Yakupoğlu, Yarkın Kamil; Özkaya, OzanThe purpose of this study was to evaluate the clinical characteristics of 44 pediatric patients who were diagnosed as having nutcracker syndrome (NCS). We also investigated the left renal vein Doppler ultrasonography (DUS) results, to determine whether or not there was an association between clinical symptoms and DUS findings among these patients. The clinical data from 44 pediatric patients who were diagnosed as having NCS from January 2008 to December 2015 were retrospectively reviewed. We grouped the patients according to the presenting symptoms as symptomatic (loin pain; macroscopic hematuria or both) and non-symptomatic (microscopic hematuria and proteinuria were detected incidentally) and evaluated the left renal vein DUS indices in these two groups separately. Asymptomatic NCS was found in 27 (61.4%) patients; 21 (47.7%) of whom were admitted for the evaluation of proteinuria. The most frequent presenting symptoms were left flank pain (20.5%) and macroscopic hematuria (13.6%); and 2 (4.5%) patients presented with a combination of left flank pain and macroscopic hematuria. The mean ratio of the diameter of the hilar portion of the left renal vein (LRV) to that of the aortomesenteric portion was 4.36 +/- 1.55. The mean ratio of the peak velocity (PV) between the two sites of the LRV was 7.32 +/- 2.68 (3.1-15.6). The differences in the ratio of the diameters were statistically significant between the two groups and significantly higher in children with asymptomatic NCS (p = 0.025). The PV ratios of the LRV (p = 0.035) were significantly higher in asymptomatic children with NCS than in the symptomatic group. Our study identifies that increased compression ratio of the LRV entrapment is most observed in orthostatic proteinuria and microscopic hematuria.Öğe Periton diyalizi programında izlenen kronik böbrek yetersizlikli çocuklarda sol ventrikül geometrisinin değerlendirilmesi(DergiPark, 2020) Azak, Emine; Özkaya, OzanAmaç: Kronik böbrek yetmezliği (KBY) olan çocuklarda kardiyovasküler morbidite artmıştır. Ancak kardiyak değişikliklerin hastalığın hangi evresinde ortaya tam olarak bilinmemektedir. Bu çalışmada periton diyaliz programında izlenen son dönem böbrek yetmezliği olan çocuklarda sol ventrikül geometrisinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Periton diyalizinde izlenen 20 KBY’li çocukta ekokardiyografik ve biyokimyasal veriler değerlendirildi. Sol ventrikül kitlesi ve rölatif duvar kalınlığı hesaplandı. Kontrol grup olarak 20 sağlıklı çocuk alındı. Bulgular: Sol ventrikül kitle indeksi ve rölatif duvar kalınlığı KBY grubunda kontrol grubuna göre anlamlı olarak yüksek bulundu (sırasıyla 88.03 ± 37.09; 41.16 ± 12.52 ve 0.62 ± 0.12; 0.39 ± 0.08, p>0.05). Sol ventrikül kitle indeksi ile sistolik kan basıncı ve parathormon arasında anlamlı bir ilişki vardı (sırasıyla r=0.428, p=0.03; r=-0.501, p=0.02). KBY’li 17’sinde (%85) çocukta anormal sol ventrikül geometrisi mevcuttu. Konsantrik hipertrofi, çalışmada en sık anomal sol ventrikül geometrisiydi. Periton diyalizi olan hastaların 9’unda (%45) sol ventrikülde konsantrik hipertrofi izlendi. KBY’li çocuklarda sol ventrikül sistolik fonksiyonları normal sınırlar içindeydi (EF %65.63±6.71 ve FS %35.7±10.25). Sonuç: Sol ventrikül hipertrofisi (LVH) kronik böbrek yetmezliği olan çocuklarda ilerleyicidir. Kan basıncının ve hiperparatiroidizimin daha yakın kontrolü bu hastalarda LVH gelişimini önlemede önemli olabilir.Öğe The results of rituximab therapy in the patients with steroid dependent nephrotic syndrome(Springer, 2018) Tekcan, Demet; Aydoğ, Özlem; Gene, Gürkan; Kendirci, Nergis; Nalçacıoğlu, Hülya; Özkaya, Ozan: The patients with steroid dependent nephritic syndrome (SDNS) require prolonged steroid therapy. To reduce the side effects of prolonged steroid therapy, alternative treatments which have steroidsparing effect are required. Alternative treatments include alkylating agents such as cyclophosphamide or chlorambucil, mycophenolate mofetil (MMF), cyclosporine, and more recently rituximab (RTX).Öğe The role of alvarado and pediatric appendicitis score in acute appendicitis in children(Galenos Yayincilik, 2020) Türkmenoğlu, Yelda; Kaçar, Alper; Duras, Ensar; Kök, Sevilay; Gözübüyük, Attila Alp; Arat, Cem; Özkaya, OzanAim: Acute appendicitis (AA) is the condition that most commonly requires a surgical procedure in children presenting to the emergency department with acute abdominal pain. Alvarado and Pediatric Appendicitis scores (PAS) are the most widely used scoring systems in the diagnosis of AA in children. This study aims to evaluate the effectiveness of Alvarado and PAS scores in the diagnosis of AA in children. Materials and Methods: One hundred and two patients aged 3-17 years, who were admitted to the pediatric emergency department with acute abdominal pain and had a clinical suspicion of AA were included in this retrospective study. The demographic characteristics, laboratory and radiological findings, and Alvarado and PAS scores were obtained from the records of the patients, retrospectively. According to the results of pathology, n=48 patients for the AA group and n=54 patients for the non-AA group were identified. The AA and non-AA groups were compared in terms of PAS and Alvarado scores. Results: The mean age of the 102 patients was 9.38 +/- 3.90 years, and 62 (60.85%) of them were male. The median PAS score was 7.79 +/- 1.2 and 5.52 +/- 1.34, and the median Alvarado score was 7.98 +/- 1.14 and 5.89 +/- 1.53 in the AA and N-AA groups, respectively (p<0.001; p<0.001). For the PAS, the cut-off score was >7 with a sensitivity of 66.7%, a specificity of 94.4%, a positive predictive value (PPV) of 91.4%, and a negative predictive value (NPV) of 76.1% (p<0.001). For the Alvarado score, the cut-off was also >7, with a sensitivity of 77.1%, a specificity of 85.2%, PPV of 82.2%, and NPV of 80.7% (p<0.001). Conclusion: Although both PAS and Alvarado scores provide useful diagnostic information in patients suspected of AA, neither of them is enough to diagnose AA alone.Öğe A single center study of the patients with cystinuria(Springer, 2018) Tekcan, Demet; Aydoğ, Özlem; Genç, Gürkan; Kendirci, Nergis; Nalçacıoğlu, Hülya; Özkaya, Ozanbe partially treated with bicarbonate, bone marrow transplantation or possibly gene therapy.Öğe A single-center kidney transplantation experience in children with low weight: is low weight a contraindication?(Verduci Editore s.r.l, 2022) Eren, Eryiğit; Tokaç, Mehmet; Özkaya, Ozan; Savaş, Osman Anıl; Sümer, Aziz; Dinçkan, AyhanOBJECTIVE: Kidney transplantation (KT) might be difficult for underweight kids (under 15 kg). Our goal was to convey information on KT in underweight children. PATIENTS AND METHODS: The study’s target population consisted of children (age 18) weighing 15 kg or fewer who received KT at our facility between January 2018 and June 2021. A retrospective analysis was performed on demographic and clinical data, including age, gender, primary disease, pretransplant dialysis status, recipient weight, recipient body mass index (BMI), surgical approach type (intraperitoneal/extraperitoneal), complications, graft status (functioning/failed), patient survival, and immunological data. RESULTS: There were 94 pediatric KTs completed. Thirty-three patients were included when the selection criteria were applied. The mean recipient weight was 11.45 [6.7-15] kg, and the average patient age was 3.36 [1-7]. Three (9.9%) patients had kidney transplants from dead adult donors, whereas thirty (90.1%) patients underwent live donor kidney transplantation (LDKT). While the intraperitoneal (IPA) technique was used in 19 cases, the extraperitoneal (KT) strategy was used on 14 patients (EPA). The donor BMI was 28.24 [19.6-42] kg/m2, and the mean donor weight was 78.13 [55-109] kg. Bridectomy was necessary because five individuals experienced ileus. IPA was performed in each of these patients during LDKT. Following IPA, a 2-year-old patient with a BMI of 16 kg/m2 had renal allograft compartment syndrome and required graft nephrectomy. CONCLUSIONS: Pediatric patients weighing 15 kg or fewer can get kidney transplants successfully. Gastrointestinal problems are relatively uncommon with EPA, even though there is no agreement on the best surgical strategy.
