Yazar "Aklar, Demet Akalgan" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim Yok
    Öğe
    Assessment of Centella Asiatica Extract Containing Dual-crosslinked Gel-MA/Pec Hydrogels as Wound Dressing
    (2022) Aklar, Demet Akalgan; Albayrak, Betül; Gelal, Melisa; İzbudak, Burçin; Özkahraman, Bengi; Öztürk, Ayça Bal
    In the present work, 3D-printed wound dressings containing different amounts of Centella Asiatica (CA) extract were synthesized via dual-crosslinking method. Methacrylic anhydride modified gelatin (Gel-MA) and pectin (Pec) were chosen as the base material for dressings. A dual crosslinked network was formed with Gel-MA photo-crosslinking using Irgacure 2959 and Pectin (Pec) psychical-crosslinking using Ca++ ions. Meanwhile, the developed dual-crosslinked hydrogel dressings were characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, and mechanical, swelling, in vitro degradation as well as ex vivo bioadhesion tests. As the amount of CA in the dressing hydrogels increased, the degradation rates increased. In addition, the prepared dressings provide good bioadhesion on the chicken skin. Moreover, (3-(4,5-Dimethylthiazol- 2-yl)-2,5-Diphenyltetrazolium Bromide) (MTT) assay revealed cell viability of Gel-MA/ Pec hydrogel dressings containing CA extract. The results presented the dressings as a promising biomaterial to be used for wound healing purposes, which should be further investigated in future.
  • Küçük Resim Yok
    Öğe
    Patient Experience in Community Pharmacies from an Experiential Marketing Perspective: Structural Equation Model
    (Marmara Univ, 2023) Aklar, Demet Akalgan; Ozcelikay, Gulbin
    The main objective of this study was to model patient experience (PX) in community pharmacies as experimental marketing parameters via structural equation modeling (SEM). Our findings show that peace of mind, trust, pharmacy, customer engagement, interaction quality with the pharmacist and personnel, and atmosphere or periphery experience quality is the important component for a patient to re-visit the same pharmacy. The patient's journey to the pharmacy starts before entering the pharmacy, continues at the pharmacy, and then leaves the pharmacy. It is important to understand the touchpoint of the patient journey at a community pharmacy and the needs of the patients as well as other health services. Overall, whether it is patient experience or customer experience, both focus on people and understanding their needs as a service sector will add value to service quality. The research was conducted on 414 volunteer patients given informed consent and answered 73 items in Istanbul province. The data obtained from the questionnaire forms were analyzed using the IBM SPSS Statistics 23 package program. Confirmatory factor analysis (CFA) was applied using IBM SPSS AMOS 23 package program in the analysis of trust, pharmacy customer engagement (PCE), word of mouth (WoM), pharmacist interaction quality, personnel interaction quality, periphery experience quality, peace-of-mind (POM), and autobiographical memory parameters. Since the assumption of normality was not provided, the relationships among these items were calculated using Spearman's correlation coefficient. The results were evaluated at the significance level of p <0.05. Finally, a structural equation model was conducted to specify PX items.