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Öğe Comparison of the outcomes of spinal and general anesthesia for cesarean section in pregnant women with COVID-19(Ondokuz Mayis Universitesi, 2024) Aydin, N.; Esen, O.; Tüten, N.We aimed to examine the efficacy and safety of spinal or general anesthesia for cesarean section (C/S) delivery in parturient with coronavirus illness (COVID-19). We carried out a retrospective cohort in our tertiary care centre's anesthesiology and reanimation department. We gathered the data from the medical files of 108 pregnant women (average age: 33.44±12.65 years) with COVID-19 who underwent cesarean section (C/S) with either general (Group I, n=30) or spinal anesthesia (Group II, n=78). We compared preoperative, intraoperative, postoperative respiratory, cardiac, hematological, and biochemical indicators between spinal and general anesthesia groups. Patients in Group I were significantly older (p<0.001), had longer APTT (p=0.015), PT (p=0.005), INR (p=0.003), higher levels of AST (p=0.012), CK (p=0.001), CRP (p<0.001), as well as longer duration of ICU stay (p<0.001), and hospitalization (p<0.001). Group II had higher preoperative levels of troponin T (p=0.001). In Group I, the levels of procalcitonin (p=0.002), lactate (p<0.001), AST (p<0.010), ALT (p=0.001), CRP (p<0.001), and total bilirubin (p<0.001) were significantly higher than Group II. Group II displayed increased levels of white blood cell count (p=0.023), CK (p=0.047), and LDH (p=0.001). Our data demonstrated that the selection of the mode of anesthesia must provide safe, patient-centered care and safeguard every member of the obstetric team from COVID-19 infection. During planning for cesarean section (C/S), certain care and special precautions should be employed, and the type of anesthesia must be selected on an individualized basis. © 2024 Ondokuz Mayis Universitesi. All rights reserved.Öğe Evaluation of demographic characteristics and laboratory results of patients with Covid-19 treated in the intensive care unit(Ondokuz Mayis Universitesi, 2022) Aydin, N.; Esen, O.; Karayalçin, U.We aimed to investigate the clinical features, hemodynamic and respiratory profiles as well as prognostic outcomes of critically sick COVID-19 patients admitted to intensive care units (ICUs). This retrospective study was performed using data derived from 99 adult patients treated in the ICU. Demographic and clinical data as well as hemodynamic and respiratory profiles, therapeutic outcomes were recorded. The relationship between these features and ICU stay was sought. The average age was 65.94 ± 14.93 years (24 to 96), and 73 patients (73.7%) had comorbidities. Smokers constituted 13.1% of the Covid-19 patient population (n=13) in ICU. Thirty-one cases (31.3%) had received at least one dose of Covid-19 vaccine and 63 patients (63.6%) died in the ICU after their initial hospitalization. Blood products were utilized in 29 patients (29.3%) and delta mutation was detected in 23 (23.2%) of ICU patients. The mean duration of ICU stay was 16.90 ± 11.41 days (1 to 60). The duration of ICU stay was remarkably different between groups receiving different antibiotic regimens (p<0.001). There was no significant relationship between the duration of ICU stay and blood groups (p=0.052), systolic (p=0.572) and diastolic blood pressure (p=0.098) and initial arterial oxygen saturation (p=0.223). We detected a high mortality rate in our series with severe COVID-19 infection treated in ICU. These data are critical for understanding the impact of COVID-19 on our hospitals, identifying areas for clinical management improvement, and allowing for continuous international and temporal comparisons of COVID-19 patient outcomes. © 2022 Ondokuz Mayis Universitesi. All rights reserved.Öğe The factors affecting mortality in intensive care unit of a burns center(Pakistan Medical Association, 2023) Esen, O.; Turgut, T.; Tiryaki, C.; Yazicioglu, M.B.; Ciftci, A.; Esen, H.K.Objective: To determine the characteristics of patients, mortality-affecting factors and mortality rate in follow-up burn-injured patients in an intensive care setting at a burns treatment centre. Method: The retrospective study was conducted between May and November 2014 at Kocaeli Derince Training and Research Hospital Burn Treatment Centre, Kocaeli, Turkey, and comprised data from January 2008 to January 2013 of in-patients who had been treated at the intensive care unit. The therapy outcomes and the follow-up processes were evaluated. Data was analysed using SPSS 17. Results:Of the 381 patients, 105(27.6%) were females and 276(72.4%) were males. The overall mean age was 28.4±21.1 years. There were 52(13.6%) mortalities, while 329(86.4%) survived. The mean total body surface area was 18.3±12.9% in those who survived compared to 52±24.3% in those who died (p<0.000). The highest rate of death was observed in those aged >66 years (p<0.000). The impact of flame burns on mortality was statistically significant (p<0.05). The impact of inhalation burns, suicide, abuse, operational requirements and systemic disease on mortality was statistically significant (p<0.05). Conclusions: Older age, higher total body surface area, flame burns, presence of inhalation burn, third degree burn, suicide attempt, presence of systemic disease, duration of prolonged mechanical ventilation and operation requirements were found to be poor prognostic factors for survival in burn patients. © 2023 Pakistan Medical Association. All rights reserved.