Yazar "Kalko, Yusuf" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    Comparison of sedoanalgesia versus general anesthesia in surgical resection of carotid body tumors: a retrospective cohort study
    (JOSAM, 2021) Kalko, Yusuf; Gencer, Muzaffer; Çuğlan, Bilal; Koçyiğit, Ali
    Background/Aim: Carotid body tumors (CBTs) are very rare. There is no uniform agreement on the method of anesthesia according to the Shamblin classification. The aim of this study was to report and compare outcomes and complications of different anesthesia methods according to the Shamblin classification in patients operated for CBTs. Methods: The data of 52 patients (40 males, 12 females) diagnosed with CBT Shamblin Type 1 or Type 2 and surgically treated were enrolled. General anesthesia (Group G) and sedoanalgesia (Group S) were administered in 35 and 17 patients, respectively. We retrospectively compared the surgical outcomes and complications between the groups to evaluate which anesthetic approach was more appropriate for early recognition of complications, hemodynamic stability, and surgical satisfaction in CBT surgeries. Results Group S patients were more stable hemodynamically. Hypertension, tachycardia, hypotension were significantly more frequent in Group G (P<0.001). Intraoperative blood loss was significantly less in the Group S (P=0.024). Both patient and surgeon satisfaction scores were significantly higher in Group S (P=0.071). In Group G, transient ischemic attack developed in 1 patient, postoperative dysphagia developed in 4 patients due to possible nerve injury during resection. Deviation and ptosis of the tongue due to facial nerve damage developed in 3 patients in Group G and in 2 patients in Group S (P=0.028). Conclusions: Sedoanalgesia may be more helpful for patients compared to general anesthesia in tumor surgery of patients with CBT classified as Shamblin Type 1 and 2.
  • Küçük Resim Yok
    Öğe
    Effect of Pretreatment with Cilostazol on Spinal Cord Ischemia-reperfusion Injury in Rats
    (2021) Erkanlı Şahin, Gözde; Kalko, Yusuf; Kafa Kulaçoğlu, Ülkü
    Objective: Following the aortic aneurysm repair surgery, ischemic spinal cord injury is a substantial complication which may lead to paraplegia. This study aims to explore the protective effect of cilostazol, which is a phosphodiesterase type-3 inhibitor, against ischemic/ reperfusion-induced spinal cord injury that is experimentally forged in medulla spinalis of rats. Methods: A total of 24 rats were separated into three workgroups. The control group (n=8); the ischemic group (n=8), in which aortic clamping was performed without cilostazol administration; and finally the cilostazol-adminsistered group (n=8). Each mouse was subjected to induced ischemia for 45 min by clamping of the abdominal aorta. Afterwards, blood build up was provided by de-clamping. Serial assessments of motor and sensory functions of all rats were performed prior to the operation and, at 24 and 48 h of reperfusion, using the Tarlov and LeMay scores. Later on, spinal cord tissues were collected for histopathologic examination. Results: Tarlov scores at postoperative hours 24 and 48 tend to be significantly higher in the cilostazol-treated group than in the non-treated ischemia group (3.13±0.64 versus 1.25±0.71, p=0.0029 for the 24th hour; 2.75±0.71 versus 0.38±0.52, p=0.0016 for the 48th hour). LeMay scores at postoperative hours 24 and 48 were as well significantly higher in the cilostazol-treated group than in the non-treated ischemia group (9.13±1.13 versus 4.50±0.76, p=0.0018 for the 24th hour; 9.00±1.20 versus 3.75±0.89, p=0.0018 for the 48th hour). Histologic outcomes were strongly correlated to the neurologic outcomes. Conclusion: These results suggest that pre-ischemia cilostazol treatment has a protective effect against ischemia/reperfusion-induced spinal cord injury.