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    Comparison of Video Head Impulse Test Results of Pediatric Patients with Dizziness with Healthy Volunteers
    (Istanbul University Press, 2022) Yılmaz, E.; Yağcı, İ.; Kesimli, M.C.; Altundağ, A.
    Objective: The Video Head Impulse Test (V-HIT) is a non-invasive diagnostic test that evaluates the functions of the semicircular canals separately. This test records eye movements in response to head movements, and the vestibulo-ocular reflex gain (VOR-G) is calculated. V-HIT is frequently used in diagnosing adult patients and has been increasingly used in children in recent years. Indeed, V-HIT measurements may be useful in the diagnosis, especially in pediatric patients where vestibular pathologies are difficult to evaluate. In this study, V-HIT findings of pediatric patients with dizziness were examined, and the results were compared with healthy volunteers. Methods: Thirteen pediatric patients who applied to our clinic with dizziness and nine healthy children were included in the study. The necessary evaluations and radiological imaging were performed, and children diagnosed with any pathology were excluded. Each patient underwent GN Otometrics ICS Impulse V-HIT examination, and the results were recorded. The Video Head Impulse Test (v-HIT) results of children with vertigo were compared with those of healthy volunteers and analyzed. Results: The mean age of the patients included in the study was 10.5±3.5 years (range: 5-16). Five of these children were boys, and 8 were girls. In the control group, there were five girls and four boys, and their mean age was 9.3±3.9 years (range: 5-16). None of the children had any additional disease. When the groups were compared, the left anterior canal and left lateral canal VOR-Gs were significantly different between the patients and healthy volunteers (p=0.027 and p=0.007, respectively). No statistically significant difference was observed between the groups in terms of the right anterior canal, right lateral canal, left posterior canal, and right posterior canal VOR-G measurements (p=0.928, p=0.738, p=0.588, and p=0.780,). Conclusion: V-HIT, a non-invasive method for evaluating the etiology of vertigo in children, can be easily applied even in very young children. The use of glasses suitable for children will facilitate the procedure. © 2022, Istanbul University Press. All rights reserved.
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    Concha Bullosa as a Cause of Rhinological Halitosis
    (Istanbul University Press, 2024) Yılmaz, E.; Kesimli, M.C.; Yağcı, İ.; Altundağ, A.
    Objective: Sinonasal diseases are one of the main causes of foul breath. Disruption of mucus drainage leading to bacterial putrefaction is the leading factor of volatile organic compounds (VOCs) production. Concha bullosa (CB) is also one of the factors affecting mucus drainage. Its effect on foul breath was investigated in this study. Materials and Methods: Sixty patients were included in the study. The participants were selected from those complaining of halitosis, who have CB formation on at least one side, and pathologic VOCs, hydrogen sulfide, methylmercaptan, and dimethylsulfide levels in their OralChroma measurements. The patients were divided into two groups. Surgery was applied to 32 patients, and no treatment was given to 28 patients. The VOCs levels were evaluated using OralChroma. Results: Sixty patients with a mean age of 36.5 years were included in the study. Before and after the operation of concha bullosa and also when the surgical group and control groups were compared, the decrease in methylmercaptan values was shown to be statistically significant (p<0.05). Conclusion: Concha bullosa should be considered in the etiology of halitosis in cases with no determined cause and high methylmercaptan values. © 2024, Istanbul University Press. All rights reserved.
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    Impact of Hyberbaric Oxygen Therapy on Olfactory Function and Bulb Volume in Diabetic Patients with Olfactory Dysfunction
    (Istanbul University Press, 2023) Gürbüz, D.; Kesimli, M.C.; Bilgili, A.M.; Durmaz, H.Ö.
    Objective: Investigating the efficiency of Hyperbaric Oxygen Therapy (HBOT), recommended adjuvant therapy for diabetic neuropathy patients, in changing olfactory bulb volume and function in diabetic patients with olfactory dysfunction. Materials and methods: 12 individuals, from a pool of type-2 diabetes mellitus (DM) patients with diabetic foot, had olfactory dysfunction based on olfaction test results. Olfactory tests and Magnetic Resonance Imaging (MRI) were used to measure and evaluate olfactory bulb volume and function changes in response to HBOT in these 12 patients (comparing Group 1 to Group 2). Similar analysis was carried out to compare the findings to those of 13 healthy patients (Group 3). Results: Patients in Group 1, 2, and 3 were categorized as moderately hyposmic, mildly hyposmic, and normosmic, respectively based on olfaction test results. HBO treatment seems to be efficient as the OBV values and olfaction test results of Group 1 were significantly lower than those of Group 2. Comparison of olfactory tests shows statistically significant improvement in post-treatment odor perception. Conclusion: It has been shown that both olfactory function and OB volumes based on MRI have increased significantly after HBO therapy in diabetic patients with olfactory dysfunction. © 2023, Istanbul University Press. All rights reserved.