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    Clinical reflection of pre- and post-COVID-19 symptoms in COVID-19 patients
    (2022) Demirkol, Barış; Gül, Şule; Çortuk, Mustafa; Koç, Aysu Sinem; İlhan, Umut; Baydili, Kürşad Nuri; Çetinkaya, Erdoğan; Koç, Aysu Sinem
    Background: Hospitalized or non-hospitalized patients with Coronavirus disease-2019 (COVID-19) may exhibit different symptoms. Different symptoms of patients can give us an idea about the course of the disease. Materials and Methods: A cross-sectional questionnaire study was conducted between August and October 2021. The questionnaire was sent online to patients who had COVID-19 infection with polymerase chain reaction positivity. The following categories were included in the questionnaire: Demographic characteristics, diagnosis date, initial symptoms, predominant symptoms, treatments, presence of hospitalization requirement, ongoing symptoms after the treatment, and symptom duration. Results: Of the 596 patients, 574 (92.4%) were symptomatic at the beginning of the disease. Myalgia, fatigue, and headache were the most prominent initial symptoms. Fever and dyspnea were the most predominant symptoms that compel the patients to apply to the hospital. While dyspnea was significantly higher in hospitalized patients, fever was more common in non-hospitalized patients. Higher mean age, male gender, and comorbidity (especially chronic obstructive pulmonary disease) were found to be factors that increased hospitalization (p<0.01). Fever and fatigue were mostly seen among females, while myalgia was most prominent among men. Four hundred and seventy-seven patients (80%) had post-COVID symptoms and the most common symptoms were getting tired easily, fatigue, myalgia, and cough. However, post-COVID symptoms were most intense in the second month and there were cases with complaints up to one year. Conclusion: The majority of the COVID-19 patients in our study were symptomatic. Dyspnea and fever with higher mean age were more common in patients requiring hospitalization. Post-COVID symptoms may persist for a long time, and long-term monitoring may be beneficial.