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Öğe Effectiveness and safety transarterial embolization with bleomycin-loaded PLA/PLGA (polylactic acid)(poly[lactic-co-glycolic acid]) microspheres for treatment of vascular malformation using a porcine spleen model(Science Direct, 2019) Nurili, F.; Acar, T.; Derman, S.; Baş, A.; Caymaz, I.; Yurdaışık, Işıl; Çakıroğlu, H.; Özkanlı, S.; Aras, O.To prospectively study the effectiveness and safety of Bleomycin-loaded PLA/PLGA microparticles in the porcine spleen modelÖğe Embolization of rabbit renal arteries to test feasibility and effects of CT-visible doxorubicin-eluting montmorillonite microparticles(Science Direct, 2019) Nurili, F.; Bekaroğlu, G.; İşçi, S.; Baş, A.; Caymaz, I.; Yurdaışık, Işıl; Özkanlı, S.; Çakıroğlu, H.; Aras, O.Purpose: To develop CT-visible doxorubicin (DOX)-eluting montmorillonite microparticles for transarterial embolization.Öğe Multifunctional iron oxide nanoparticle-embedded PVP-HEC microparticles as a drug-eluting embolic material(Science Direct, 2019) Nurili, F.; Bekaroğlu, G.; İşci, S.; Caymaz, I.; Baş, A.; Özkanlı, S.; Yurdaışık, Işıl; Çakıroğlu, H.; Aras, O.To develop MRI imageable novel HEC-PVP-magnetic embolic particles intended for transcatheter arterial chemoembolization and magnetic ablationÖğe Retrospective analysis of the first 50 emergency/elective surgical cases in terms of mortality and morbidity in COVID-19 pandemic hospital in Istanbul(Edizioni Luigi Pozzi, 2020) Pekşen, C.; Aktokmakyan, T.V.; Savaş, O.A.; Datli, A.; Nurili, F.; Yurdaişik, I.; Bozkurtgil N.2019-nCoV currently named SARS-CoV-2 is a highly pathogenic Coronavirus identified in Wuhan China in December 2019. Turkey declared the first case relatively late compared to Asian and European countries on March 11, as the first SARS-CoV-2 infection in Turkey. In this study, we aimed to determine patients’ outcomes in 50 surgeries done in the incubation period of SARS-CoV-2 in our hospital. METHODS: We retrospectively analyzed the clinical data of 50 patients who underwent surgeries during the incubation period of CoVid-19 at Istinye University Gaziosmanpasa Medical Park Hospital in Istanbul, from March 2 to April 11, 2020. RESULTS: The age of 50 patients range was 21 to 73, and the median age was 43.32 (64%) patients were women. The median length of hospital stay is 2.6 days (1-21). Operations at various difficulty levels were also performed on patients with co-morbidities. No complication or mortality was observed except for 1 patient, and the ICU requirement of that patient was also due to high energy trauma. CONCLUSION: Although contrary claims have been made in various studies; it is the primary duty of us surgeons to operate CoVid-19 positive/suspicious patients safely and without any contamination, and on the other hand, to continue their operations without victimizing negative patients. In this pilot study, we would like to emphasize with necessary and adequate measures these can be achieved. © 2020, Edizioni Luigi Pozzi. All rights reserved.Öğe Transarterial embolization of prostate with biodegradable flutamide-loaded PLA/PLGA microspheres for benign prostate hyperplasia: preliminary study in a normal swine model(Science Direct, 2019) Nurili, F.; Acar, T.; Derman, S.; Baş, A.; Yurdaışık, Işıl; Özkanli, S.; Caymaz, I.; Çakıroğlu, H.; Aras, O.Purpose: To prospectively evaluate whether transarterial embolization with biodegradable flutamide-loaded PLA/PLGA microspheres with sustained-release properties in the prostate of swine can induce shrinkage in the volume of prostatic tissue. Flutamide is a strong nonsteroidal antiandrogen acts as selective, competitive and silent antagonist.
