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    Effect of nutritional status on the presence of malnutrition and quality of life in patients with gastrointestinal tract cancer
    (Bayrakol Medical Publisher, 2023) Ulker, Mutlu Tuce; Guveli, Hakan
    Aim: Cancers affecting the gastrointestinal tract are common worldwide, and cancers of the stomach and pancreas have a poor prognosis. Supporting nutritional status before, during and after cancer treatment improves the effectiveness of treatment and quality of life. Malnutrition is seen in cancer patients due to loss of appetite, nausea, vomiting, diarrhea, chewing or swallowing problems, taste and smell changes, therefore malnutrition should be evaluated in all cancer patients and appropriate nutritional support should be initiated. In this study, we aimed to evaluate the effect of nutritional status on malnutrition and quality of life in patients with gastrointestinal system cancer. Material and Methods: The cross-sectional study included 60 patients who received gastrointestinal system treatment and met the inclusion criteria. The Quality of Life Test (EORTC QLQ-C30) and NRS-2002 were administered to the patients by the investigator using a face-to-face method. Socio-demographic information, anthropometric measurements and biochemical findings were obtained from patient files with hospital permission. Results: In the study, most of the patients were at risk of malnutrition; however, no significant correlation was found between NRS 2002 and quality of life and cancer stages. There was an inverse relationship between albumin levels and malnutrition risk (p<0.05). Discussion: Cancer patients are at risk of malnutrition due to the heavy treatment brought by the disease, therefore, malnutrition risks should be determined in the early period, appropriate nutritional support should be provided and their quality of life should be improved.
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    Evaluation of the effect of gluten-free diet and Mediterranean diet on autoimmune system in patients with Hashimoto's thyroiditis
    (Wiley, 2024) Ulker, Mutlu Tuce; Colak, Gozde Aritici; Bas, Murat; Erdem, Mustafa Genco
    Hashimoto's thyroiditis is an autoimmune disease in which thyroid cells are attacked through cell-and antibody-mediated immune processes. A gluten-free diet reduces antibody concentration and regulates thyroid autoimmunization. Mediterranean diet reduces oxidative stress. This study evaluates the short-term effects of Mediterranean, gluten-free, and Mediterranean gluten-free dietary patterns on thyroid function and autoantibody levels of patients. The 40 patients with Hashimoto's thyroiditis included in the study were randomly divided into four groups (defined as gluten-free, Mediterranean, Mediterranean gluten-free, and controls) for 12 weeks. Thyroid function tests, autoantibody levels, and food consumption were recorded at the beginning and end of the study. There was no statistically significant difference in TSH levels of the groups before the intervention, but a statistically significant difference was found afterward (p < 0.05). Free T-3 hormone levels showed a statistically significant difference across the groups before and after the intervention (p < 0.05). Free T-3 hormone levels increased significantly in all intervention groups after the intervention, with the highest increase in the Mediterranean group (p < 0.05). In the intervention groups, anti-TPO and anti-Tg levels decreased after the intervention; however, this difference was not significant across groups (p > 0.05). In addition, body weight, body mass index, waist and hip circumference averages decreased significantly in all intervention groups compared with controls (p < 0.05). The study achieved an increase in Free T-3 hormone levels in the intervention groups. The most marked difference was seen in the Mediterranean gluten-free diet model, which may be due to the anti-inflammatory effect of both Mediterranean and gluten-free diets and the loss of body weight as a result of the intervention.
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    Growth and development impact of sustainable nutrition education: An experimental study
    (Wiley, 2024) Ulker, Mutlu Tuce; Simsek, Aysegul; Hacioglu, Gizem Elvan; Kurt, Aysu; Erken, Serra; Yildiz, Beyza
    Healthy societies are formed by learning and maintaining sustainable healthy eating behaviors from childhood. The aim of this study was to determine the effect of short-term sustainable nutrition education on growth and development parameters of preschool children. This study is an experimental design with pretest-posttest control group. This study was carried out in two kindergartens between February 2022 and June 2023 in Turkey. The education group received 4 months of dietary behavior training. The dietary scale and anthropometric measurements were administered at the first and last meetings. Data were analyzed with 95% confidence interval. The study was completed with 174 children. A statistically significant difference was found, especially in body weight (p < 0.05) and body weight percentile values (p < 0.05) in the posttest of the education group. A statistically significant difference (p < 0.05) was found between the groups in the eating behavior scale posttest score. Nutrition education in schools is important in promoting healthy eating habits. Nutrition education improves eating behavior positively. To maintain healthy eating behaviors, however, the continuity of education is necessary. In addition, as growth and development are physical processes, it is recognized that growth and development cannot be assessed by nutrition alone.