EFFICACY AND SAFETY OF POSTOPERATIVE INTRAVESICAL ADMINISTRATION OF TRANEXAMIC ACID AFTER TRANSURETHRAL RESECTION OF THE PROSTATE*
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Istanbul University Press
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: To evaluate the safety and efficacy of postoperative intravesical administration of tranexamic acid after transurethral resection of the prostate. Material and Method: The data of 112 patients who underwent surgery for lower urinary tract symptoms associated with benign prostatic obstruction (BPO) were retrospectively analysed. We formed two groups: Group 1 consisted of 57 patients who received tranexamic acid by irrigation fluid after the operation; group 2 consisted of 55 patients who did not receive tranexamic acid. Demographic data of patients and prostate characters, as well as operative and postoperative data were analysed. Postoperative bleeding in all patients was evaluated using the haemoglobin levels at the preoperative, and at 0- and 24-h postoperative were evaluated and noted. Result: The mean ages of the patients were 66.9±7.2 (55-81) years in the intervention group, and those in the control group were 68.6±7.6 (55-80) years. There were no significant differences between the groups for demographic data, prostate volume and International Prostate Symptom Score (IPSS). The reduction in Hb at 24 hours postoperatively was greater in the control group compared to the tranexamic acid (TXA) group. Statistically significant differences were found between the two groups in terms of postoperative haemoglobin decrease, bladder irrigation time and total amount of irrigation fluid. There were no statistically significant differences between each group regarding the operation, weight of resected adenoma, hospitalization time and catheter removal time. Conclusion: A postoperative follow-up process with less bleeding and complications is possible with tranexamic acid added to the intravesical irrigation fluid used after transurethral prostate resection (TURP) surgery. © 2023 Istanbul University Press. All Rights Reserved.
Açıklama
Anahtar Kelimeler
İrrigation Fluid, Postoperative Bleeding, Tranexamic Acid, Transurethral Resection Of The Prostate
Kaynak
Istanbul Tip Fakultesi Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
86
Sayı
4
