Aksoy, Süleyman HilmiYurdaışık, IşılTimurağaoğlu, Ayşen2022-06-152022-06-1520222619-9793https://doi.org/10.4274/imj.galenos.2022.40771https://hdl.handle.net/20.500.12713/2905Introduction: The study aimed to quantify the ionizing radiation exposure of patients with hematologic malignancy who underwent hematopoietic stem cell transplantation (HSCT). Methods: This was a retrospective evaluation of the adult patients who underwent allogeneic or autologous HSCT for hematologic malignities in a single center between January 2016 and September 2020. All radiological imaging procedures involving ionizing radiation screened study participants. The study period covered both the pre- and post-transplantation phases. A typical cumulative effective dose (CED) was used to calculate the exposed ionizing radiation in units of millisieverts (mSv). Results: A total of 120 patients (females 38.3%, mean age: 52.2 +/- 15.6 years) were included. Autologous HSCT was performed in 66 patients (55%), whereas 54 patients (45%) underwent allogeneic HSCT. Patients with acute myeloid leukemia and acute lymphoblastic leukemia comprised 53.7% and 31.5% of allogeneic HSCT, respectively. Autologous HSCT was mainly performed in patients with multiple myeloma (47%) and non-hodgkin lymphoma (34.8%). The median total CED was 11.85 mSv (interquartile range: 4.08-19.78). The median CED of allogeneic HSCT patients was significantly higher than that of the autologous HSCT group. The vast majority of the total CED (92.3%) comes from computed tomography imaging procedures. In the entire groups, 92 patients (76.7%) received a low dose (<20 mSv), whereas 26 patients (21.7%) received a moderate dose (>20-50 mSv) ionizing radiation. Conclusion: One-third of all HSCT patients received a moderate ionizing radiation dose. Allogeneic HSCT patients had significantly higher median CED than autologous counterparts.eninfo:eu-repo/semantics/openAccessComputed TomographyCumulative Effective DoseIonizing RadiationRadiation ExposureHematopoietic Stem Cell TransplantationArticle232119124WOS:000803867300008N/A10.4274/imj.galenos.2022.40771520567