Donmez, Emin ErhanElci, ErkanElci, Gulhan2024-05-192024-05-1920241364-57061365-2931https://doi.org10.1080/13645706.2024.2309960https://hdl.handle.net/20.500.12713/5307Background and aim: Comparison of the applicability, safety, and surgical outcomes of total vaginal NOTES hysterectomy (TVNH) using natural orifice transluminal endoscopic surgery, which is considered a natural orifice surgery for hysterectomy with bilateral salpingo-oophorectomy (HBSO) in virgin transgender men, with conventional total laparoscopic hysterectomy (TLH). Material and methods: A retrospective cohort study was conducted between 2019 and 2021. The results of transgender male individuals who underwent HBSO operations using TVNH (n = 21) were compared with those who underwent operations using TLH (n = 62). Results: TVNH was performed in 21 individuals, while TLH was performed in 62 individuals. Patients in the TVNH approach group had a longer operation duration than those in the TLH group (p = .001). Patients in the TVNH group experienced less pain at two hours (5 +/- 1.56), six hours (4 +/- 1.57), 12 h (2 +/- 0.91), and 24 h (1 +/- 0.62) postoperatively (p = .001). The postoperative hospitalization duration was shorter in the TVNH group (1.6 +/- 1.01) than in the TLH group (2.9 +/- 0.5) (p = .001). Conclusions: For the HBSO operation of female-to-male transgender individuals, TVNH, which is completely endoscopically performed, can be preferred and safely conducted as an alternative surgical method to conventional laparoscopy.eninfo:eu-repo/semantics/closedAccessLaparoscopic HysterectomyNotesTvnhVaginal Notes HysterectomyVirgin Transgender MenArticle38353421WOS:0011621416000012-s2.0-85185684186N/A10.1080/13645706.2024.2309960Q2