Akın, Hasan YalımSeval, Güldane CengizAtilla, Pınar AtacaYurdakul Mesutoğlu, PınarOtlu, TanerAnlıaçık, RıdvanDalva, KlaraGürman, GünhanBeksaç, Meral2021-11-292021-11-292021Akin, H. Y., Seval, G. C., Atilla, P. A., Mesutoglu, P. Y., Otlu, T., Anliacik, R., ... & Beksac, M. (2021). P-068: Haplotypes rich in activating killer-cell immnuglobulin-like receptor genes are associated with delay on age of myeloma onset. Clinical Lymphoma Myeloma and Leukemia, 21, S76.2152-26502152-2669https://hdl.handle.net/20.500.12713/2286Natural killer (NK) cells are known for their anti-tumoral cytotoxic effects. Effector NK-cell functions are controlled by interactions between inhibitory and activating killer-cell immnuglobulin-like receptors (iKIRs and aKIRs) on NK cells in the presence of human leukocyte antigen (HLA) class I ligands on target cells. The aim of this study was to investigate the frequency of KIR genotypes with/without their cognate ligands among myeloma (MM) patients compared to a healthy population.eninfo:eu-repo/semantics/closedAccessHaplotypes rich in activating killer-cell immnuglobulin-like receptor genes are associated with delay on age of myeloma onsetOther21Supplement 2S76S76WOS:000717640800129Q3