Demir, Fulya AvcıBingöl, GülsümErsoy, İbrahimArslan, AkifErsoy, PınarDemir, MeltemÜnlü, Serkan2025-04-182025-04-182024Demir, F. A., Bingöl, G., Ersoy, İ., Arslan, A., Ersoy, P., Demir, M., & Ünlü, S. (2024). The Relationship between Frontal QRS-T Angle and Vitamin D Deficiency. Medicina, 60(5), 776.1010-660X1648-9144http://dx.doi.org/10.3390/medicina60050776https://hdl.handle.net/20.500.12713/6675Background and Objectives: A deficiency in serum 25-hydroxyvitamin D levels is associated with a number of cardiovascular situations, such as high blood pressure, heart failure, atherosclerotic heart disease, and peripheral artery disease. The frontal QRS-T angle has recently been proposed as a marker of ventricular repolarization. A wider frontal QRS-T angle has been positively correlated with adverse cardiac events. The objective of our study was to examine the association between serum 25-hydroxyvitamin D level and the frontal QRS-T angle. Materials and Methods: A total of 173 consecutive patients aged 18-60 years undergoing routine cardiology check-up evaluation, and not receiving concurrent vitamin D treatment were included in the study. Patients were classified in three groups, depending on their vitamin D levels, and categorized as follows: Group 1-deficient (<20 ng/mL), Group 2-insufficient (20-29 ng/mL), or Group 3-optimal (>= 30 ng/mL). The frontal QRS-T angle was determined using the automated reports generated by the electrocardiography machine. Results: The average age of participants was 45.8 (+/- 12.2) years, and 55.5% of participants were female (p < 0.001). Individuals with low vitamin D concentrations exhibited a wider frontal QRS-T angle. It was determined that vitamin D level is an independent predictive factor for the frontal QRS-T angle. Conclusions: As the levels of 25-hydroxyvitamin D decrease, repolarization time assessed by frontal QRS-T angle is widened. Our findings indicate that lower concentrations of vitamin D may increase the susceptibility to ventricular arrhythmia.eninfo:eu-repo/semantics/openAccessElectrocardiographyFrontal QRS-T AngleVitamin DArticle60519WOS:0012316864000012-s2.0-85194185796Q110.3390/medicina60050776Q1