Sofu, HakanGümüşsuyu, GürkanGuler, OlcayUcpunar, HanifiDuman, SerdaCamurcu, Yalkin2021-09-062021-09-062021Sofu, H., Gumussuyu, G., Guler, O., Ucpunar, H., Duman, S., & Camurcu, Y. (2021). Lesion size and varus malalignment are the major determinants leading to poorer clinical outcomes after combined microfracture treatment for focal cartilage lesions during anterior cruciate ligament reconstruction. Archives of Orthopaedic and Trauma Surgery, 1-9.0936-80511434-3916https://doi.org/10.1007/s00402-021-04138-xhttps://hdl.handle.net/20.500.12713/2020The purposes of this study were to evaluate the clinical effects of microfracture (MFX) performed for Outerbridge grade 3 or 4 focal cartilage lesion during the same surgery with arthroscopic anterior cruciate ligament (ACL) reconstruction and to analyze the major determinants of these potential effects on the clinical outcome. The clinical and radiographic data of 119 patients were evaluated. The mean follow-up time was 32.6 +/- 6 months. Isolated arthroscopic ACL reconstruction was performed in 70 patients (Group 1), whereas MFX for Outerbridge grade 3 or 4 chondral lesion during ACL surgery was performed in 49 patients (Group 2). Visual analogue scale (VAS) score, Lysholm knee score, and Tegner activity scale were the instruments used as outcome measures to evaluate the clinical status of the patients. Routine X-ray and MRI were also performed for all patients pre-operatively as well as at the latest follow-up visit. Lineer regression analysis was performed to determine major factors predicting the poorer clinical outcome. Clinical outcomes were similar between isolated ACL reconstruction and combined procedure. On the other hand, according to lineer regression analysis, cartilage lesion size > 2 cm(2) and > 5 degrees of varus alignment were detected as the major determinants leading to poorer outcomes in combined ACL reconstruction and MFX. Level of evidence: III - Retrospective Comparative Study.eninfo:eu-repo/semantics/closedAccessCartilage LesionMicrofractureACL ReconstructionArthroscopyKnee LigamentsArticle34448044WOS:0006894946000012-s2.0-85113522982Q210.1007/s00402-021-04138-xQ1