Dashti, F.Ghaffari, A.Seyfollahi, A.Arasteh, B.2024-05-192024-05-1920241380-7501https://doi.org/10.1007/s11042-024-18945-yhttps://hdl.handle.net/20.500.12713/4195The lack of symptoms in the early stages of liver disease may cause wrong diagnosis of the disease by many doctors and endanger the health of patients. Therefore, earlier and more accurate diagnosis of liver problems is necessary for proper treatment and prevention of serious damage to this vital organ. We attempted to develop an intelligent system to detect liver failure using data mining and artificial neural networks (ANN), this approach considers all factors impacting patient identification and enhances the probability of success in diagnosing liver failure. We employ multilayer perceptron neural networks for diagnosing liver failure via a liver patient dataset (ILDP). The proposed approach using the backpropagation algorithm, improves the diagnosis rate, and predicts liver failure intelligently. The simulation and data analysis outputs revealed that the proposed method has 99.5% accuracy, 99.65% sensitivity, and 99.57% specificity, making it more accurate than Previous related methods. © The Author(s) 2024.eninfo:eu-repo/semantics/openAccessAntigenDiagnosisHealthcareLiver DisorderMultilayer Perceptron Neural NetworkArticle2-s2.0-8518831958110.1007/s11042-024-18945-yQ1