Tuten, NevinTuten, AbdullahGöok, KorayHamzaoglu, KubraBulut, HuriMalik, EduardGuralp, Onur2022-02-212022-02-212022Tüten N, Tuten A, Gök K, Hamzaoglu K, Bulut H, Malik E, Guralp O. Serum Vasostatin-1 Level is Increased in Women with Preeclampsia. Z Geburtshilfe Neonatol. 2022 Feb 18.0948-23931439-1651https://doi.org/10.1055/a-1747-3738https://hdl.handle.net/20.500.12713/2497Objective: To evaluate the serum vasostatin-1 levels in preeclamptic and non-preeclamptic pregnant women. Materials and methods: Thirty consecutive women with mild preeclampsia and sixty consecutive women with severe preeclampsia were compared with ninety gestational age-matched (±1 week) non-preeclamptic pregnant women with an appropriate-for-gestational-age (AGA) fetus. Results: Mean serum vasostatin-1 was significantly higher in women with preeclampsia than gestational age-matched controls. Mean serum vasostatin-1 was significantly higher in the mild preeclampsia group compared to its gestational age-matched control group, and in the severe preeclampsia group compared to its gestational age-matched control group. There was no significant difference in mean serum vasostatin-1 levels between the mild and severe preeclampsia groups, and in severe early- and severe late-onset preeclampsia groups. Serum vasostatin-1 had positive correlations with systolic and diastolic blood pressure. Conclusion: Serum vasostatin-1 was significantly higher in women with preeclampsia compared to those of the gestational age-matched controls. There was no significant difference in mean serum vasostatin-1 levels between the mild and severe preeclampsia groups and severe early- and severe late-onset preeclampsia groups.eninfo:eu-repo/semantics/closedAccessArticle35181881WOS:0007575534000022-s2.0-85125407114Q410.1055/a-1747-3738Q3