Karakılıç, ErsenAyçiçek, BerçemTuna, Mazhar MüslümBaşaran, Mehtap NavdarÜnal, MustafaBarker, DilekGülar, Serdar2021-05-312021-05-312021Karakılıç, E., Unal, I. M., Ayçiçek, I. B., Berker, I. D., Tuna, I. M. M., Güler, I. S., & Başaran, I. M. N. (2021). THYROID VOLUME IN YOUNG MALES WITH IDIOPATHIC HYPOGONADOTROPIC HYPOGONADISM VERSUS YOUNG HEALTHY MALES. Nobel Medicus Journal, 17(1).1305-2381https://hdl.handle.net/20.500.12713/1772Objective: To evaluate the differences in thyroid volume and thyroid functions between male patients newly diagnosed with idiopathic hypogonadotropic hypogonadism (IHH) and healthy males. Material and Method: A total of 51 consecutively diagnosed male patients with IHH (mean age: 30.1 +/- 8.9 years) and 36 body mass index (BMI)- and age-matched healthy controls (mean age: 31.3 +/- 5.9 years) were included in the study. All the subjects resided in the same region where mild iodine deficiency was present. Patients with thyroid diseases were excluded. Follicle-stimulating hormone (FSH), luteinizing hormone (LH), IGF-1, prolactin, cortisol, total testosterone, free testosterone, free T4 (fT4), free T3 (fT3), TSH, anti-TPO, and anti-TG were evaluated. Thyroid volumes (TV) were measured using a high-resolution. ultrasound operated by an experienced endocrinologist. Results: FSH, LH, total testosterone and free testosterone were lower in patients with IHH than in the control subjects (p<0.05). TSH, fT4, fT3, anti-TPQ and anti-TG were found to be similar in both groups (p>0.05). Thyroid volume of patients with IHH (mean value of TV=11, 0 +/- 6.2 mL) was significantly smaller than in the control subjects (mean value of TV=18, 6 +/- 8.1 mL) (p=0.001). Conclusion: Young males with newly diagnosed IHH have smaller thyroid volume than healthy males. Thyroid function tests were similar in both groups.eninfo:eu-repo/semantics/closedAccessHypogonadismThyroid GlandGonadotropinsThyroid Function TestsArticle1715458WOS:000648280400007Q4Q4