Güven, Deniz CanAksun, Melek SerenÇakır, İbrahim YahyaKılıçkap, SaadettinKertmen, Neyran2021-09-012021-09-012021Guven, D. C., Aksun, M. S., Cakir, I. Y., Kilickap, S., & Kertmen, N. (2021). The association of BMI and sarcopenia with survival in patients with glioblastoma multiforme. Future Oncology, (0).1479-66941744-8301https://hdl.handle.net/20.500.12713/2015Background: The association between obesity and sarcopenia (via temporal muscle thickness) with overall survival (OS) has been evaluated in several glioblastoma multiforme studies, however, the data are inconclusive. Methods: The authors conducted meta-analyses via the generic inverse-variance method with a random-effects model. Results: In the pooled analysis of five studies, including 973 patients, patients with lower temporal muscle thickness had significantly decreased OS (HR: 1.62, 95% CI: 1.16-2.28, p = 0.005). The pooled analysis of five studies, including 2131 patients, demonstrated decreased OS in patients with lower BMI compared with patients with obesity (HR: 1.45, 95% CI: 1.12-1.88, p = 0.005). Conclusion: Readily available body composition parameters could be used for prognosis prediction and to aid in treatment decisions in patients with glioblastoma multiforme.eninfo:eu-repo/semantics/closedAccessGlioblastoma MultiformeObesityPrognosisSarcopeniaTemporal Muscle ThicknessArticle34409854WOS:0006862304000012-s2.0-85118411396Q310.2217/fon-2021-0681Q1