Aktaş, Ranan, Sr.Akbulut, ZeynepMaraş, Hatice, Jr.Çakıl, Yaprak DönmezKayalı, DamlaKaragöz Köroğlu, AyçaSitar, Mustafa ErinçKısakol, BatuhanBaysan, Mehmet2020-11-062020-11-0620200270-91391527-3350https://hdl.handle.net/20.500.12713/1177Background: Hippo-YAP pathway is a key modulator in liver development, egeneration and the metabolism . Cell density, cell contact, the actin cytoskeleton, and extracellular matrix (ECM) composition have been shown to be involved in regulation of this pathway . The intervention of this pathway in hepatocellular carcinoma remains a central focus . The study aimed to examine how YAP1 integrate mechanical cues with the response to signal transduction pathways and to multiple aspects of cell behavior, proliferation, protein/lipid secretion, apoptosis/necrosis, adhesion, and stemness .eninfo:eu-repo/semantics/closedAccessArticle72239A239AWOS:000574027000377Q1