Yalta, KenanYetkin, ErtanYalta, Tülin2020-08-302020-08-302020Yalta, K., Yetkin, E., & Yalta, T. (2020). Recurrent takotsubo cardiomyopathy: Further insights into morphological patterns. CARDIOVASCULAR PATHOLOGY, 48. https://doi.org/10.1016/j.carpath.2020.1072251054-88071879-1336https://doi.org/10.1016/j.carpath.2020.107225https://hdl.handle.net/20.500.12713/362Yetkin, Ertan (isu author)Takotsubo cardiomyopathy (TTC) has been widely recognized as a specific form of transient myocardial dysfunction, and is well known to have a potential recurrence risk following the index event [1-11]. In a recent systematic review [3], certain factors in-cluding female gender, temporal proximity to the first TTC event, lower body mass index (BMI) and an existing mid-ventricular gra-dient (MVG) (potentially suggestive of a mechanical basis for TTC evolution) have been suggested as fundamental predictors of TTC recurrence. On the other hand, extreme adrenergic discharge in the setting of index TTC (regardless of its association with these sug-gested predictors) might potentially be regarded as central to the evolution of future TTC recurrences, and might present with in-direct clinical signs including left ventricular outflow tract (LVOT) gradient and coronary slow flow (CSF) in this setting [5-7]. In their recently published article [1], Ahmadjee A, et al have reported a female patient who had suffered a recurrent TTC episode with a completely different morphological pattern compared with the in-dex TTC (classical followed by a reverse TTC pattern). Accordingly; we would like to make a few comments on this interesting case and potential implications of morphological patterns in the setting of TTC recurrenceseninfo:eu-repo/semantics/closedAccessLetter4832460038WOS:0005457945000082-s2.0-85085207033Q310.1016/j.carpath.2020.107225Q1