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Now showing items 2253-2272 of 3182
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Paediatric orthopaedics through paintings
(British Editorial Soc Bone Joint Surgery, 2018)Purpose Some famous artistic representations created throughout the centuries can reveal a hidden or mysterious diagnosis of some diseases and these paintings have always drawn the attention of physicians interested in ... -
Pain ladder of the palliative care center for cancer pain management. A new perspective from Turkey based on EFIC standards
(KARE PUBL, 2021)It is known that the pathophysiology and treatment strategies of cancer pain, acute and chronic pain, which are not clearly classified in the traditional approach to pain management, are different. Cancer pain is the most ... -
Palladium (II) complex and thalidomide intercept angiogenic signaling via targeting FAK/Src and Erk/Akt/PLC gamma dependent autophagy pathways in human umbilical vein endothelial cells
(Elsevier, 2021)The current study assessed the effects of the thalidomide and palladium (II) saccharinate complex of terpyridine on the suppression of angiogenesis-mediated cell proliferation. The viability was assessed after treatment ... -
Palladium (II) complex enhances ROS-dependent apoptotic effects via autophagy inhibition and disruption of multiple signaling pathways in colorectal cancer cells
(2021)Background: Inhibition of autophagy is reported to be a therapeutically effective strategy in overcoming the resistance that is a deadly outcome in cancer. One of the most common reasons for chemo-resistance to treatment ... -
Palladium(II) and platinum(II) saccharinate complexes with bis(diphenylphosphino)methane/ethane: synthesis, S-phase arrest and ROS-mediated apoptosis in human colon cancer cells
(Royal Soc Chemistry, 2018)New neutral [M(sac)(2)(diphos)] and cationic [M(diphos)(2)](sac)(2) complexes, where M = Pd-II or Pt-II, sac = saccharinate, and diphos = 1,1-bis(diphenylphosphino)methane (dppm) or 1,2-bis(diphenylphosphino)ethane (dppe), ... -
A palladium(II)-saccharinate complex of terpyridine exerts higher anticancer potency and less toxicity than cisplatin in a mouse allograft model
(Lippincott Williams & Wilkins, 2017)The main aim of this study is to assess the safety and antitumor efficacy of a palladium(II) (Pd)-saccharinate complex with terpyridine. To characterize the Pd(II) complex in vitro, its cytotoxicity was evaluated using a ... -
Palliative posterior instrumentation versus corpectomy with cage reconstruction treatment for thoracolumbar pathological fracture
(Korean Soc Spine Surgery, 2019)Study Design: Single-center, retrospective cohort study. Purpose: We aimed to evaluate and compare the clinical outcomes in patients who underwent palliative posterior instrumentation (PPI) versus those who underwent ... -
Pandemi döneminin ana haber bültenlerindeki izleyici katılımı üzerindeki rolü: Fox tv örneği
(TR- Dizin, 2022)Our article examines the impact of the pandemic period on audience engagement in broadcast news through the concept of feedback. The uncertainty and increasing need for information during the pandemic have affected the ... -
Pandemi sürecinde eczane çalışanlarının yaşadıkları iş stresinin uyumsal performans üzerindeki etkisinde iş-aile çatışmasının aracılık rolü
(İstinye Üniversitesi / Sosyal Bilimler Enstitüsü, 2021)Bu araştırmanın amacı pandemi sürecinde eczane çalışanlarının iş streslerinin uyumsal performans üzerindeki etkisinde iş-aile çatışmasının aracılık rolüne sahip olup olmadığını tespit etmektir. Bu kapsamda İstanbul’da ... -
The pandemic, statistics for 2020, journal targets and gastric cancer
(TURKISH SURGICAL ASSOC, 2021)When I was appointed as the editorial coordinator of the journal, I pointed out our goals to be reached and the most important one was increasing the quality and visibility of the journal. During the last two years, I ... -
Pankreas kanserinde yeni sentezlenen pt(ıı) sakkarinat kompleksi kimyasal bileşiğinin, antikanser etkinliğinin araştırılması
(İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2020)Pankreas kanseri genellikle hastalığın son evrelerinde belirti veren sinsi bir hastalıktır. Bununla birlikte günümüzün en ölümcül 4. kanser türü olarak bilinmektedir. Kemoterapi tedavisi sonrasında hücrelerin kazandığı ... -
Panvigilance: integrating biomarkers in clinical trials for systems pharmacovigilance
(Mary Ann Liebert, Inc, 2019)Drug safety and pharmacovigilance are rapidly changing with biomarkers and new technologies such as artificial intelligence. However, we need new ideas and application contexts for integration of biomarkers and emerging ... -
Papillary urothelial carcinoma arising from ureterocele: is it a rare occurrence?
(College of Physicians and Surgeons Pakistan, 2022)Various hydronephrotic, dysplastic or clinical pathologies can accompany ureterocele, which is a cystic dilatation of the intravesical part of the submucosal ureter. However, the development of cancer in the ureterocele ... -
The paracrine immunomodulatory interactions between the human dental pulp derived mesenchymal stem cells and CD4 T cell subsets
(Academic Press Inc Elsevier Science, 2016)Mesenchymal stem cells (MSCs) have strong immunomodulatory properties, however these properties may show some differences according to the tissue type of their isolate. In this study we investigated the paracrine interactions ... -
Paradigm shifts in terms of vascular emergencies during COVID-19 outbreak: an expert opinion report
(2020)Coronavirus disease-2019 (COVID-19) has become a global threat. The entire population is now under the risk. Healthcare providers are concerned about handling an increased number of COVID-19 patients in limited capacities ... -
A parallel hybrid PSO-GA algorithm for the flexible flow-shop scheduling with transportation
(Elsevier Ltd, 2022)In this paper, a Mixed-Integer Linear Programming (MILP) model to simultaneously schedule jobs and transporters in a flexible flow shop system is suggested. Wherein multiple jobs, finite transporters, and stages with ... -
The parameters to estimate postoperative severe complications classified through clavien-dindo after upper abdominal surgery in patients with primary and recurrent ovarian cancer
(Via Medica, 2019)Objectives: The more surgical effort and performing extensive upper abdominal surgery (UAS) are often required to accomplish the highest rates of optimally cytoreduction in patients with ovarian cancer. Nonetheless, the ... -
Parliamentarism from ottoman empire to the present and interventions to the parliamentary regime - an analysis on military memorandum, military coup and military coup initiatives
(Ege Univ, Fac Economics & Admin Sciences, 2019)Although Ottoman Empire passed to the parliamentary regime with the First Constitutional Era, this process was short-lived. After more than 30 years of oppression in 1908, the transition to the parliamentary regime was ... -
Partial wave analysis of J/ψ →γη η
(American Physical Society, 2022)Using a sample of (10.09±0.04)×109 J/ψ events collected with the BESIII detector, a partial wave analysis of J/ψ→γη η is performed. The masses and widths of the observed resonances and their branching fractions are reported. ... -
Paternalist liderlik ve örgüt kültürü ilişkisi : Sakarya Üniversitesi örneği
(2019)Paternalist liderlik şefkat ve otoriteyi birleştiren bir liderlik anlayışını ifade eder. Hofstede’nin kültürel boyutları bağlamında ise alanda öne çıkan görüş, paternalist liderliğin belirsizlikten sakınma ve güç aralığı ...
