Browsing by Author "Okten, Salih"

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In-silico pharmacokinetic and affinity studies of piperazine/morpholine substituted quinolines in complex with GAK as promising anti-HCV agent

Andac, Cenk A.; Cakmak, Osman; Okten, Salih; Caglar-Andac, Sena; Isildak, Ibrahim (WORLD SCIENTIFIC PUBL CO PTE LTD, 2021)

Piperazine/morpholine derivatives of quinoline substituted at positions C-3, C-6 and C-8 has been previously prepared by SNAr reactions of 3,6,8-tribromoquinoline (1) under microwave or conventional heating reaction ...
Quinoline-based promising anticancer and antibacterial agents, and some metabolic enzyme inhibitors

Okten, Salih; Aydın, Ali; Kocyigit, Umit Muhammet; Cakmak, Osman; Erkan, Sultan; Andac, Ahmet Cenk; Taslimi, Parham; Gulcın, Ilhami (Wiley-VCH Verlag, 2020)

A series of substituted quinolines was screened for their antiproliferative, cytotoxic, antibacterial activities, DNA/protein binding affinity, and anticholinergic properties by using the 3-(4,5-dimethylthiazol-2-yl)-2,5 ...