Browsing by Department "İstinye Üniversitesi"
Now showing items 1-20 of 73
-
A549 ve BEAS-2B hücre hatlarında borik asitin apoptoz yolağındaki genlerin ekspresyon düzeylerine etkisinin incelenmesi
(İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2021)Akciğer kanseri, dünyadaki en yaygın kanser türü olmakla beraber tüm kanser ölümlerinin bir numaralı nedeni olmaya devam etmektedir. Apoptoz, bir dizi sinyal iletim kaskadları ve hücresel proteinler tarafından düzenlenen ... -
Açık kalp ameliyatı sonrası erken dönemde nörofizyolojik fasilitasyon tekniklerinin pulmoner fonksiyon, respiratuar kas gücü, fonksiyonel kapasite üzerine etkileri
(İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2021)Çalışmamız açık kalp ameliyatı geçiren bireylerde nörofizyolojik fasilitasyon tekniklerinin fonksiyonel kapasite ve solunum fonksiyonları üzerine etkilerini incelemek amacıyla planlandı. Çalışmaya açık kalp ameliyatı ... -
Akciğer kanserinde borik asitin apoptotik etkisinin incelenmesi
(İstinye Üniversitesi / Sağlık Bilimleri Enstitü, 2021)Akciğer kanseri, dünyada en çok görülen kanser türü olup, kansere bağlı ölüm sebepleri arasında birinci sırada bulunmaktadır. Akciğer kanserine çözüm bulunması amacıyla, tedaviye yönelik çalışmalar yapılmakta, farklı ... -
Analysis of adnexal masses which are operated in gynecologic oncology clinic
(2018)Objective: Abnormal adnexal masses are a common gynecologic problem that affects women of all ages. Although many of these masses are benign, the primary aim of diagnostic evaluation is to exclude malignancy. In this trial, ... -
Association of the kynurenine pathway metabolites with clinical, cognitive features and IL-1 beta levels in patients with schizophrenia spectrum disorder and their siblings
(ELSEVIER, 2021)Objective: There is evidence suggesting that tryptophan (TRP)-kynurenine (KYN) pathway dysregulation is involved in the pathophysiology of schizophrenia and is regulated by inflammatory cytokines. The study investigate for ... -
Bilim tarihi, kültürel zaman ve Fuat Sezgin
(2019)Fuat Sezgin’in İslam Dünyasında yapılmış olan bilim ve teknoloji konusundaki kapsamlı çalışmaları, sadece sıradan bir bilim tarihi açısından değil, kültür tarihi açısından da son derece önemlidir. Sıradan bilim ve teknoloji ... -
Biology-oriented drug synthesis and evaluation of secnidazole esters as novel enzyme inhibitors
(Wiley, 2021)The identification of novel compounds that can inhibit physiologically and metabolically important drug targets or enzymes has prime importance in medicinal chemistry. With this aim, a range of secnidazole esters 1–30 were ... -
A brief reconnoitre about effects of MMP9 on aortic dissection
(DergiPark, 2021)Objective: Matrix metalloproteinases (MMPs) are the extracellular ma-trix regulators that frequently investigate cardiovascular diseases and cancer metastasis. Our study aimed to examine specific polymorphisms in the MMP9 ... -
A case report on recurrent cotyledonoid dissecting leiomyoma
(2019)Cotyledonoid dissecting leiomyoma is an extremely rare variant of uterine leiomyomas. Although they are pathologically benign, they manifest as sarcomatoids because of their appearance. A 34-year-old single patient was ... -
A case with a delayed diagnosis of extrafacial rosacea
(Ortadogu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2019)Rosacea is a chronic, inflammatory skin disorder involving the central part of the face. There are four main subtypes of the disease which are most commonly seen; but also, when the disease involves other parts of the body ... -
Clinical results of anterior cruciate ligament reconstruction with bone-patellar tendon-bone autograft: a prospective study
(2018)Aim: Anterior cruciate ligament(ACL) injury is the most common ligament injury of knee. Gold standard treatment of ACL rupture is reconstruction of ligament with autograft or allograft. There is still controversy in graft ... -
Comparison of microfluid sperm sorting chip and density gradient methods for use in intrauterine insemination cycles
(Elsevier Science Inc, 2019)Objective: To compare the effect of microfluiding sperm sorting chip and density gradient methods on ongoing pregnancy rates (PRs) of patients undergoing IUI. Design: Retrospective cohort study. Setting: Hospital IVF unit. ... -
COVID-19 pandemic: a glimpse into newly diagnosed hypertensive patients
(LIPPINCOTT WILLIAMS & WILKINS, 2021)The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as an immediate and global problem just within a few months after its first description ... -
COVID-19-associated mucormycosis: case report and systematic review
(Elsevier Inc., 2021)Background: Increasing number of patients with COVID-19-associated mucormycosis have been reported, especially from India recently. We have described a patient with COVID-19-associated mucormycosis and, searched and analyzed ... -
Cytotoxic effect, spectroscopy, DFT, enzyme inhibition, and moleculer docking studies of some novel mesitylaminopropanols: antidiabetic and anticholinergics and anticancer potentials
(Elsevier, 2021)β-Amino alcohols (2–4) used in this study were re-synthesized in accordance with our previous study. All compounds were characterized by the combination of NMR, UV–Vis, IR experimental and theoretical spectral data. Then, ... -
Design and optimization of a novel wind-powered liquefied air energy storage system integrated with a supercritical carbon dioxide cycle
(WILEY, 2021)In this paper, a novel liquefied air energy storage (LAES) system driven by wind energy and natural gas, integrated with a two-stage supercritical carbon dioxide cycle is proposed and investigated. Three different sensible ... -
Development and in vitro evaluation of biocompatible pla-based trilayer nanofibrous membranes for the delivery of nanoceria: a novel approach for diabetic wound healing
(MDPI, 2021)The attempts to explore and optimize the efficiency of diabetic wound healing’s promotors are still in progress. Incorporation of cerium oxide nanoparticles (nCeO2) in appropriate nanofibers (NFs) can prolong and maximize ... -
Does type 2 diabetes mellitus have an impact on postoperative early, mid-term and late-term urinary continence after robot-assisted radical prostatectomy?
(Mary Ann Liebert, Inc, 2019)Objective: We evaluated the effect of diabetes mellitus (DM) on urinary continence after robotic radical prostatectomy (RARP). Patients and Methods: Overall, 99 patients with DM and 213 patients without DM who underwent ... -
Dysregulation of MS4A3 and PRDX5 gene expression in multiple myeloma patients
(AKAD DOKTORLAR YAYINEVI, 2021)Multiple myeloma (MM) is a disease in which plasma cells increase clonally. We aimed to investigate the comparison of our transcriptome data in MM, MGUS (Monoclonal gammopathy of undetermined significance) and control ... -
Dysregulation of MS4A3 and PRDX5 gene expression in multiple myeloma patients
(UHOD - Uluslararasi Hematoloji Onkoloji Dergisi, 2021)Multiple myeloma (MM) is a disease in which plasma cells increase clonally. We aimed to investigate the comparison of our transcriptome data in MM, MGUS (Monoclonal gammopathy of undetermined significance) and control ...
