Browsing by Department "İstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Temel Bilimleri Bölümü"
Now showing items 1-20 of 24
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Advancements and future directions in the antibacterial wound dressings - a review
(2021)Wound repair is a complex process that has not been entirely understood. It can conclude in several irregularities. Hence, designing an appropriate wound dressing that can accelerate the healing period is critical. Infections, ... -
Aloe vera-based antibacterial porous sponges for wound dressing applications
(SPRINGER, 2021)The antibacterial sponges with high macroporosity, high interconnectivity and high biocompatibility is a significant concern for wound healing applications. In this work, novel Aloe vera (AV) based sponges were developed ... -
Avokadonun (persea americana) caenorhabditis elegans termotoleransı üzerine etkilerinin incelenmesi
(DergiPark, 2020)Amaç: Yaşlanma neredeyse tüm organizmalar için kaçınılmaz bir biyolojik süreçtir. Yaşlandıkça, kronik hastalıklara (obezite, diyabet, kardiyovasküler hastalıklar, kanser, Alzheimer vb.) yakalanma riski de artmaktadır. Bu ... -
Controlled release profile of 5-fluorouracil loaded P(AAM-co-NVP-co-DEAEMA) microgel prepared via free radical precipitation polymerization
(Springer, 2018)A new microgel was prepared by free radical precipitation polymerization of acrylamide (AAM), 1-vinyl-2-pyrrolidone (NVP) and 2-(diethylamino)ethyl methacrylate (DEAEMA) to be used for the controlled drug release. The ... -
Current strategies and future perspectives of skin-on-a-chip platforms: innovations, technical challenges and commercial outlook
(Bentham Science Publ Ltd, 2018)The skin is the largest and most exposed organ in the human body. Not only it is involved in numerous biological processes essential for life but also it represents a significant endpoint for the application of pharmaceuticals. ... -
Design of an amphiphilic hyperbranched core/shell-type polymeric nanocarrier platform for drug delivery
(Scientific Technical Research Council Turkey-Tubitak, 2020)An amphiphilic core/shell-type polymer-based drug carrier system (HPAE- PCL-b-MPEG), composed of hyperbranched poly(aminoester)-based polymer (HPAE) as the core building block and poly(ethylene glycol)-b-poly(epsilon-caprolactone) ... -
Development and characterization of oxaceprol-loaded poly-lactide-co-glycolide nanoparticles for the treatment of osteoarthritis
(Wiley, 2020)Oxaceprol is well-defined therapeutic agent as an atypical inhibitor of inflammation in osteoarthritis. In the present study, we aimed to develop and characterize oxaceprol-loaded poly-lactide-co-glycolide (PLGA) nanoparticles ... -
Differential interactome proposes subtype-specific biomarkers and potential therapeutics in renal cell carcinomas
(MDPI, 2021)Abstract: Although many studies have been conducted on single gene therapies in cancer patients, the reality is that tumor arises from different coordinating protein groups. Unveiling perturbations in protein interactome ... -
Evolution and clinical translation of drug delivery nanomaterials
(Elsevier Sci Ltd, 2017)With the advent of technology, the role of nanomaterials in medicine has grown exponentially in the last few decades. The main advantage of such materials has been exploited in drug delivery applications, due to their ... -
Functionalized 2-(hydroxyethyl) methacrylate (HEMA)-co-acrylamide (AAm) hydrogels: kinetic and isotherm modelling analysis on the removal of Cu(II) Ions
(Prints Publications Pvt Ltd, 2019)A functionalized hydrogel composed of 2-(hydroxyethyl) methacrylate (HEMA) and acrylamide (AAm) was synthesized by amination and saponification reactions, respectively, and its functionality was examined for the elimination ... -
In-vitro bioactivity investigation of sol-gel derived alumina-bovine hydroxyapatite (Bha) composite powders
(Gazi Universitesi, 2020)Alumina (α-Al2O3) and hydroxyapatite (HA, Ca10(PO4)6(OH)2) are well-known for being clinically successful bioceramic materials. In this work, in-vitro biological characterization of the sol-gel alumina-bovine hydroxyapatite ... -
İpek fibroin/polivinil alkol esaslı ilaç taşıyıcı yara örtüleri
(2020)Bu çalışmanın amacı, potansiyel yara örtüsü olarak ilaç taşıyıcı-yeni bir karboksil modifiyeli poli(vinil alkol)-çapraz bağlı ipek fibroin esaslı hidrojel filmi (İF/PVA) geliştirmektir. Çapraz bağlı hidrojellerin hazırlanması ... -
Oküler doku yapıştırıcıları
(DergiPark, 2020)Özet: Kornea yaraları cerrahi, enfeksiyonlardan ve travmatik yaralanmalardan kaynaklanmaktadır. Bu yaralar geleneksel olarak naylon sütürler kullanılarak onarılmaktadır. Kornea bölgesindeki yaralanmanın şekline ve derecesine ... -
The repertoire of glycan alterations and glycoproteins in human cancers
(2021)Cancer as the leading cause of death worldwide has many issues that still need to be addressed. Since the alterations on the glycan compositions or/and structures (i.e., glycosylation, sialylation, and fucosylation) are ... -
Selective targeting of signet ring cell adenocarcinomas
(Churchill Livingstone, 2019)Many epithelial tumors, especially signet-ring cell adenocarcinomas, produce huge amounts of mucin glycoproteins that fill cytoplasm and push nucleus to the periphery, giving a signet ring like structure to the cell. Mucin ... -
Sponge-like chitosan-based nanostructured antibacterial material as a topical hemostat
(Wiley, 2019)In this study, chitosan/alginic acid/zinc oxide (CHI/AA/ZnO) nanostructured hydrogel sponges were fabricated by incorporating ZnO nanoparticles (<100 nm) into polymer matrix to develop a new potential biomaterial for ... -
Synthesis of Ion-imprinted alginate based beads: selective adsorption behavior of nickel (II) Ions
(Springer, 2018)Ni(II) imprinted and non-imprinted bioadsorbent alginate beads were prepared, and utilized in the selective adsorption of Ni(II) ions. The optimum adsorption capacity were 6.00mmolg(-1) at 500ppm initial metal ion concentration ... -
Synthesis, characterization and VOCs adsorption kinetics of diethylstilbestrol-substituted metallophthalocyanines
(World Sci Publ Co Inc, 2019)Compound (4,4'-hex-3-ene-3,4-diyl)bis(4,1-phenylene)bis(oxy)diphthalonitrile 3 was synthesized by the reaction of 4-nitrophthalonitrile 1 and diethylstilbestrol 2 in dry DMF in presence of dry K2CO3 . New mononuclear ... -
Synthesis, characterization, and DFT study of novel metallo phtalocyanines with four carboranyl clusters as photosensitisers for the photodynamic therapy of breast cancer cells
(Elsevier, 2019)The synthesis and characterization of novel Zn(II) and Co(II) phthalocyanines 4 and 5, respectively containing four o-carboranyl units (40 boron atoms, 32.5% boron by weight) at the peripheral positions are described. The ... -
Synthesis, characterization, DFT study, conductivity and effects of humidity on CO2 sensing properties of the novel tetrakis- [2-(dibenzylamino)ethoxyl] substituted metallophthalocyanines
(Elsevier Science Sa, 2020)Novel tetrakis[2-(dibenzylamino)ethoxyll substituted nickel (II), cobalt (II) and manganese (II) phthalocyanines were synthesized by using 4-(2-(dibenzylamino)ethoxy)phthalonitrile with corresponding metal salts in 2-N, ...
