Browsing by Department "İstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Temel Bilimleri Bölümü"
Now showing items 1-20 of 37
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Advancements and future directions in the antibacterial wound dressings - a review
(2021)Wound repair is a complex process that has not been entirely understood. It can conclude in several irregularities. Hence, designing an appropriate wound dressing that can accelerate the healing period is critical. Infections, ... -
Aloe vera-based antibacterial porous sponges for wound dressing applications
(SPRINGER, 2021)The antibacterial sponges with high macroporosity, high interconnectivity and high biocompatibility is a significant concern for wound healing applications. In this work, novel Aloe vera (AV) based sponges were developed ... -
Anthelmintic activity of nigella sativa against caenorhabditis elegans
(HORIZON RESEARCH PUBLISHING, 2021)Increasing resistance against classical anthelmintic drugs makes discovering new anthelmintic compounds from natural plants important. Nigella sativa (N. sativa) is used as a medicinal plant overall the world and is known ... -
Application of magnetic resonance imaging in liver biomechanics: a systematic review
(Frontiers, 2021)MRI-based biomechanical studies can provide a deep understanding of the mechanisms governing liver function, its mechanical performance but also liver diseases. In addition, comprehensive modeling of the liver can help ... -
Avokadonun (persea americana) caenorhabditis elegans termotoleransı üzerine etkilerinin incelenmesi
(DergiPark, 2020)Amaç: Yaşlanma neredeyse tüm organizmalar için kaçınılmaz bir biyolojik süreçtir. Yaşlandıkça, kronik hastalıklara (obezite, diyabet, kardiyovasküler hastalıklar, kanser, Alzheimer vb.) yakalanma riski de artmaktadır. Bu ... -
Boric acid-impregnated silk fibroin/gelatin/hyaluronic acid-based films for improving the wound healing process
(Journal of Applied Polymer Science, 2021)Recently, with the progression in wound dressings, the importance of the biocompatible material with enhanced features for potential applications in the biomedical field has been more developed. Current strategies focus ... -
Can lactate dehydrogenase inhibition be increased efficiency of 1,25(oh) 2 d 3 vitamin in prostate cancer animal model?
(Wiley, 2022)The Warburg effect explains that the cancer cell's metabolism is programmed based on anaerobic glycolysis to support the proliferation and anabolic growth of cancer cells. LDH-A is the form of LDH found in cancer cells, ... -
Controlled release profile of 5-fluorouracil loaded P(AAM-co-NVP-co-DEAEMA) microgel prepared via free radical precipitation polymerization
(Springer, 2018)A new microgel was prepared by free radical precipitation polymerization of acrylamide (AAM), 1-vinyl-2-pyrrolidone (NVP) and 2-(diethylamino)ethyl methacrylate (DEAEMA) to be used for the controlled drug release. The ... -
Current strategies and future perspectives of skin-on-a-chip platforms: innovations, technical challenges and commercial outlook
(Bentham Science Publ Ltd, 2018)The skin is the largest and most exposed organ in the human body. Not only it is involved in numerous biological processes essential for life but also it represents a significant endpoint for the application of pharmaceuticals. ... -
Current strategies for the regeneration of skeletal muscle tissue
(MDPI AG, 2021)Traumatic injuries, tumor resections, and degenerative diseases can damage skeletal muscle and lead to functional impairment and severe disability. Skeletal muscle regeneration is a complex process that depends on various ... -
Design of an amphiphilic hyperbranched core/shell-type polymeric nanocarrier platform for drug delivery
(Scientific Technical Research Council Turkey-Tubitak, 2020)An amphiphilic core/shell-type polymer-based drug carrier system (HPAE- PCL-b-MPEG), composed of hyperbranched poly(aminoester)-based polymer (HPAE) as the core building block and poly(ethylene glycol)-b-poly(epsilon-caprolactone) ... -
Development and characterization of oxaceprol-loaded poly-lactide-co-glycolide nanoparticles for the treatment of osteoarthritis
(Wiley, 2020)Oxaceprol is well-defined therapeutic agent as an atypical inhibitor of inflammation in osteoarthritis. In the present study, we aimed to develop and characterize oxaceprol-loaded poly-lactide-co-glycolide (PLGA) nanoparticles ... -
Differential interactome proposes subtype-specific biomarkers and potential therapeutics in renal cell carcinomas
(MDPI, 2021)Abstract: Although many studies have been conducted on single gene therapies in cancer patients, the reality is that tumor arises from different coordinating protein groups. Unveiling perturbations in protein interactome ... -
Enzyme-mediated Alleviation of Peroxide Toxicity in Self-oxygenating Biomaterials
(2022)Oxygen releasing biomaterials can facilitate the survival of living implants by creating environments with a viable oxygen level. Hydrophobic oxygen generating microparticles (HOGMPs) encapsulated calcium peroxide (CPO) ... -
Evolution and clinical translation of drug delivery nanomaterials
(Elsevier Sci Ltd, 2017)With the advent of technology, the role of nanomaterials in medicine has grown exponentially in the last few decades. The main advantage of such materials has been exploited in drug delivery applications, due to their ... -
Flavonoid contents antioxidant and neuroprotective activities of crataegus monogyna jacq. leaves and flowers
(PARLAR SCIENTIFIC PUBLICATIONS (P S P), 2021)Antioxidant activities of Crataegus species' leaves and fruits so far have been reported in literature, however, several factors ranging from plant part(s), harvest season, the species and the geographical origin of the ... -
Functionalized 2-(hydroxyethyl) methacrylate (HEMA)-co-acrylamide (AAm) hydrogels: kinetic and isotherm modelling analysis on the removal of Cu(II) Ions
(Prints Publications Pvt Ltd, 2019)A functionalized hydrogel composed of 2-(hydroxyethyl) methacrylate (HEMA) and acrylamide (AAm) was synthesized by amination and saponification reactions, respectively, and its functionality was examined for the elimination ... -
In-vitro bioactivity investigation of sol-gel derived alumina-bovine hydroxyapatite (Bha) composite powders
(Gazi Universitesi, 2020)Alumina (α-Al2O3) and hydroxyapatite (HA, Ca10(PO4)6(OH)2) are well-known for being clinically successful bioceramic materials. In this work, in-vitro biological characterization of the sol-gel alumina-bovine hydroxyapatite ... -
İpek fibroin/polivinil alkol esaslı ilaç taşıyıcı yara örtüleri
(2020)Bu çalışmanın amacı, potansiyel yara örtüsü olarak ilaç taşıyıcı-yeni bir karboksil modifiyeli poli(vinil alkol)-çapraz bağlı ipek fibroin esaslı hidrojel filmi (İF/PVA) geliştirmektir. Çapraz bağlı hidrojellerin hazırlanması ... -
Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications
(Royal Society of Chemistry, 2021)Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient ...
