Browsing by Department "ISU, Rektörlük, Uygulama ve Araştırma Merkezleri, Moleküler Kanser Uygulama ve Araştırma Merkezi"
Now showing items 1-5 of 5
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A brief reconnoitre about effects of MMP9 on aortic dissection
(DergiPark, 2021)Objective: Matrix metalloproteinases (MMPs) are the extracellular ma-trix regulators that frequently investigate cardiovascular diseases and cancer metastasis. Our study aimed to examine specific polymorphisms in the MMP9 ... -
Etoposide loaded SPION-PNIPAM nanoparticles improve the in vitro therapeutic outcome on metastatic prostate cancer cells via enhanced apoptosis
(2020)Prostate cancer is among the leading causes of death worldwide because its metastatic form is a deadly disease. Therefore, the development of new chemotherapeutics is of immense importance. Nanoparticle technology seems ... -
The improved killing of both androgen-dependent and independent prostate cancer cells by etoposide loaded SPIONs coupled with NIR irradiation
(Royal Society of Chemistry, 2022)Etoposide (Eto) is a toxic drug that shows promise in treating prostate cancer (PCa) but confers significant side effects, and has poor solubility and bioavailability. Nanoparticles are quite successful in overcoming such ... -
Palladium (II) complex enhances ROS-dependent apoptotic effects via autophagy inhibition and disruption of multiple signaling pathways in colorectal cancer cells
(2021)Background: Inhibition of autophagy is reported to be a therapeutically effective strategy in overcoming the resistance that is a deadly outcome in cancer. One of the most common reasons for chemo-resistance to treatment ... -
Water-soluble silver(I) complexes with N-donor benzimidazole ligands containing an imidazolium core: stability and preliminary biological studies
(Royal Society of Chemistry, 2021)Herein, we report the synthesis, characterisation and preliminary biological evaluation of two novel silver(I) complexes of type [AgL2](NO3)3 (3 and 4) with ionic N-donor benzimidazoles. The complexes have been synthesized ...
