Browsing by Subject "NAMD"

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Identifying and elucidating the roles of Y198N and Y204F mutations in the PAH enzyme through molecular dynamic simulations

Aslan, Tolga; Yenenler-Kutlu, Asli; Gerlevik, Umut; Aktuglu Zeybek, Ayse Cigdem; Kiykim, Ertugrul; Sezerman, Osman Ugur (Taylor And Francis, 2021)

ABSTRACT Phenylketonuria is an autosomal recessive disorder caused by mutations in the phenylalanine hydroxylase gene. In phenylketonuria causes various symptoms including severe mental retardation. PAH gene of a classical ...