Browsing by Author "Acar, Havva Yagci"

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Development of near-infrared region luminescent N-acetyl-L-cysteine-coated Ag2S quantum dots with differential therapeutic effect

Buz, Pelin Turhan; Duman, Fatma Demir; Erkisa Genel, Merve; Demirci, Gozde; Ari, Ferda; Ulukaya, Engin; Acar, Havva Yagci (Future Medicine Ltd, 2019)

Aim: N-acetyl-L-cysteine (NAC) is a free radical scavenger. We developed NAC-coated Ag2S (NAC-Ag2S) quantum dot (QD) as an optical imaging and therapeutic agent. Materials & methods: QDs were synthesized in water. Their ...
Etoposide loaded SPION-PNIPAM nanoparticles improve the in vitro therapeutic outcome on metastatic prostate cancer cells via enhanced apoptosis

Erkisa Genel, Merve; Ari, Ferda; Ulku, Irem; Khodadust, Rouhollah; Yar, Yasemin; Acar, Havva Yagci; Ulukaya, Engin (2020)

Prostate cancer is among the leading causes of death worldwide because its metastatic form is a deadly disease. Therefore, the development of new chemotherapeutics is of immense importance. Nanoparticle technology seems ...
Folic acid-conjugated cationic Ag2S quantum dots for optical imaging and selective doxorubicin delivery to HeLa cells

Duman, Fatma Demir; Erkisa, Merve; Khodadust, Rouhullah; Ari, Ferda; Ulukaya, Engin; Acar, Havva Yagci (Future Medicine Ltd, 2017)

We aim to develop folic acid ( FA)-conjugated cationic Ag2S near-infrared quantum dots (NIRQDs) for the delivery of doxorubicin (DOX) selectively to folate receptor (FR)-positive cancer cells to achieve enhanced drug ...