Browsing by Author "Akbal Dağıstan, Özlem"

Now showing items 1-2 of 2

Pulmonary delivery of favipiravir in rats reaches high local concentrations without causing oxidative lung injury or sSystemic side effects

Akbal Dağıstan, Özlem; Sevim, Mustafa; Şen, Leyla Semiha; Başarır, Nur Sena; Çulha, Meltem; Ertürk, Aybige; Fael, Hanan; Kaptan, Engin; Sancar, Serap; Mülazımoğlu Durmuşoğlu, Lütfiye; Yeğen, Berrak C; Yıldız Peköz, Ayça (MDPI, 2022)

Favipiravir displays a rapid viral clearance, a high recovery rate and broad therapeutic safety; however, its oral administration was associated with systemic side effects in susceptible patients. Considering that the ...
Pulmonary delivery of favipiravir inhalation solution for COVID-19 treatment: in vitro characterization, stability, in vitro cytotoxicity, and antiviral activity using real time cell analysis

Yıldız Peköz, Ayça; Akbal Dağıstan, Özlem; Fael, Hanan; Çulha, Meltem; Ertürk, Aybige (TAYLOR & FRANCIS, 2022)

Favipiravir, an RNA-dependent RNA polymerase (RdRp) inhibitor, is used to treat patients infected with influenza virus and most recently with SARS-CoV-2. However, poor accumulation of favipiravir in lung tissue following ...