Browsing by Author "Akgun, Oguzhan"
Now showing items 1-4 of 4
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Effective and new potent drug combination: histone deacetylase and Wnt/beta-catenin pathway inhibitors in lung carcinoma cells
Akgun, Oguzhan; Erkisa Genel, Merve; Ari, Ferda (Wiley, 2019)Lung cancer is the most commonly diagnosed cancer worldwide with a high mortality rate. In this study, the therapeutic effect of combination valproic acid and niclosamide was investigated on human lung cancer cell line. ... -
Epigenetic modulators combination with chemotherapy in breast cancer cells
Ari, Ferda; Napieralski, Rudolf; Akgun, Oguzhan; Magdolen, Viktor; Ulukaya, Engin (Wiley, 2021)Despite the concerning adverse effects on tumour development, epigenetic drugsare very promising in cancer treatment. The aim of this study was to compare the dif-ferential effects of standard chemotherapy regimens (FEC: ... -
Investigation of the efficacy of paclitaxel on some miRNAs profiles in breast cancer stem cells
Erturk, Elif; Ari, Ferda; Akgun, Oguzhan; Ulukaya, Engin; Kucukali, Cem Ismail; Zeybek, Umit (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2021)Understanding of the functions of microRNAs in breast cancer and breast cancer stem cells have been a hope for the development of new molecular targeted therapies. Here, it is aimed to investigate the differences in the ... -
Quantification of DNA damage products by gas chromatography tandem mass spectrometry in lung cell lines and prevention effect of thyme antioxidants on oxidative induced DNA damage
Aybastier, Onder; Dawbaa, Sam; Demir, Cevdet; Akgun, Oguzhan; Ulukaya, Engin; Ari, Ferda (Elsevier Science Bv, 2018)Lung cancer has a high treatment cost and poor prognosis in comparison to other types of cancers. This work was involved in studying oxidative DNA base damage inhibition. Accordingly, standard carvacrol, thymol, thymoquinone ...
