Browsing by Author "Alarcin, Emine"
Now showing items 1-11 of 11
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Advancements and future directions in the antibacterial wound dressings - a review
Bal-Ozturk, Ayca; Ozkahraman, Bengi; Ozbas, Zehra; Yasayan, Gokcen; Tamahkar, Emel; Alarcin, Emine (2021)Wound repair is a complex process that has not been entirely understood. It can conclude in several irregularities. Hence, designing an appropriate wound dressing that can accelerate the healing period is critical. Infections, ... -
Current strategies and future perspectives of skin-on-a-chip platforms: innovations, technical challenges and commercial outlook
Bal-Ozturk, Ayca; Miccoli, Beatrice; Avci-Adali, Meltem; Mogtader, Ferzaneh; Sharifi, Fatemeh; Cecen, Berivan; Yasayan, Gokcen; Braeken, Dries; Alarcin, Emine (Bentham Science Publ Ltd, 2018)The skin is the largest and most exposed organ in the human body. Not only it is involved in numerous biological processes essential for life but also it represents a significant endpoint for the application of pharmaceuticals. ... -
Design of an amphiphilic hyperbranched core/shell-type polymeric nanocarrier platform for drug delivery
Bal Ozturk, Ayca; Oguz, Nesrin; Tekarslan Sahin, Hande; Emik, Serkan; Alarcin, Emine (TUBITAK, 2022)An amphiphilic core/shell-type polymer-based drug carrier system (HPAE- PCL-b-MPEG), composed of hyperbranched poly(aminoester)-based polymer (HPAE) as the core building block and poly(ethylene glycol)-bpoly(ε-caprolactone) ... -
Development and characterization of oxaceprol-loaded poly-lactide-co-glycolide nanoparticles for the treatment of osteoarthritis
Alarcin, Emine; Demirbag, Caglar; Karsli-Ceppioglu, Seher; Kerinnoglu, Oya; Bal-Ozturk, Ayca (Wiley, 2020)Oxaceprol is well-defined therapeutic agent as an atypical inhibitor of inflammation in osteoarthritis. In the present study, we aimed to develop and characterize oxaceprol-loaded poly-lactide-co-glycolide (PLGA) nanoparticles ... -
Development of mucoadhesive modified kappa-carrageenan/pectin patches for controlled delivery of drug in the buccal cavity
Ozkahraman, Bengi; Ozbas, Zehra; Yasayan, Gokcen; Puren Akguner, Zeynep; Yarimcan, Filiz; Alarcin, Emine; Bal-Ozturk, Ayca (Wiley, 2021)In this study, modified kappa-carrageenan/pectin hydrogel patches were fabricated for treatment of buccal fungal infections. For this purpose, kappa-carrageenan-g-acrylic acid was modified with different thiolated agents ... -
The effect of thiol functional groups on bovine serum albumin/chitosan buccal mucoadhesive patches
Bal-Ozturk, Ayca; Alarcin, Emine; Ozbas, Zehra; Ozkahraman, Bengi (Editions de Sante, 2022)In this research, the effect of thiol functional groups on bovine serum albumin (BSA)/chitosan (Chi) based buccal mucoadhesive patch was investigated. Thiolated BSA (BSA-SH) was prepared via 2-mercaptoethanol. FTIR and 1H ... -
Gelatin methacryloyl/nanosilicate nanocomposite hydrogels encapsulating dexamethasone with a tunable crosslinking density for bone repair
Alarcin, Emine; Dokgoz, Ayse Begum; Akguner Puren, Zeynep; Seki, Hatice Kubra; Bal Ozturk, Ayca (Editions de Sante, 2022)Despite various strategies have been proposed to accelerate bone regeneration, the treatment of bone defects in critical size still remains a clinical challenge. In this study, we fabricated nanocomposite gelatin methacryloyl ... -
Natural polymers for wound dressing applications
Yasayan, Gokcen; Alarcin, Emine; Bal-Ozturk, Ayca; Avci-Adali, Meltem (Elsevier, 2022)Wound care is a hot topic in recent years. Recent wound treatment regimens use dressings fabricated from natural materials due to their significant advantages compared to traditional or synthetic dressings. Because of their ... -
Optimization of methacrylated gelatin /layered double hydroxides nanocomposite cell-laden hydrogel bioinks with high printability for 3D extrusion bioprinting
Alarcin, Emine; Izbudak, Burcin; Yuce Erarslan, Elif; Domingo, Sherif; Tutar, Rumeysa; Titi, Kariman; Kocaaga, Banu; Guner, F. Seniha; Bal Ozturk, Ayca (John Wiley and Sons Inc, 2022)Layered double hydroxides (LDHs) offer unique source of inspiration for design of bone mimetic biomaterials due to their superior mechanical properties, drug delivery capability and regulation cellular behaviors, particularly ... -
Photo-crosslinkable chitosan and gelatin-based nanohybrid bioinks for extrusion-based 3D-bioprinting
Yuce-Erarslan, Elif; Tutar, Rumeysa; Izbudak, Burcin; Alarcin, Emine; Kocaaga, Banu; Guner, F. Seniha; Emik, Serkan; Bal-Ozturk, Ayca (TAYLOR & FRANCIS AS, 2021)In the last decade, 3D-bioprinting has attracted attention due to its capability to produce complex scaffolds. The selection of suitable biomaterials for the bioink design is very important for the success of 3D-bioprinting. ... -
Selection of natural biomaterials for micro-tissue and organ-on-chip models
Bal-Ozturk, Ayca; Cecen, Berivan; Yasayan, Gokcen; Alarcin, Emine; Kocak, Polen; Tutar, Rumeysa; Kozaci, Leyla Didem; Ryon Shin, Su; K Miri, Amir (2022)The desired organ in micro-tissue models of organ-on-a-chip (OoC) devices dictates the optimum biomaterials, divided into natural and synthetic biomaterials. They can resemble biological tissues' biological functions and ...
