Browsing by Author "Alharbi, Ahmad M."

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Antiamoebic properties of ceftriaxone and zinc-oxide-cyclodextrin-conjugated ceftriaxone

Makhlouf, Zinb; Akbar, Noor; Khan, Naveed Ahmed; Shah, Muhammad Raza; Alharbi, Ahmad M.; Alfahemi, Hasan; Siddiqui, Ruqaiyyah (MDPI, 2022)

Acanthamoeba castellanii is a ubiquitous free-living amoeba capable of instigating keratitis and granulomatous amoebic encephalitis in humans. Treatment remains limited and inconsistent. Accordingly, there is a pressing ...
Effect of microgravity on the gut microbiota bacterial composition in a hindlimb unloading model

Siddiqui, Ruqaiyyah; Qaisar, Rizwan; Khan, Naveed Ahmed; Alharbi, Ahmad M.; Alfahemi, Hasan; Elmoselhi, Adel (MDPI, 2022)

We utilised a ground-based microgravity hindlimb unloading (HU) mouse model to elucidate the gut microbiota bacterial changes in mice under a simulated microgravity environment. Four-month-old, male C57/Bl6 mice were ...
Imidazothiazole derivatives exhibited potent effects against brain-eating amoebae

Siddiqui, Ruqaiyyah; El-Gamal, Mohammed, I; Boghossian, Anania; Saeed, Balsam Qubais; Oh, Chang-Hyun; Abdel-Maksoud, Mohammed S.; Alharbi, Ahmad M.; Alfahemi, Hasan; Khan, Naveed Ahmed (MDPI, 2022)

Naegleria fowleri (N. fowleri) is a free-living, unicellular, opportunistic protist responsible for the fatal central nervous system infection, primary amoebic meningoencephalitis (PAM). Given the increase in temperatures ...