Browsing by Author "Ashrafizadeh, Milad"
Now showing items 1-18 of 18
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Chitosan-based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy
Ashrafizadeh, Milad; Hushmandi, Kiavash; Mirzaei, Sepideh; Bokaie, Saied; Bigham, Ashkan; Makvandi, Pooyan; Rabiee, Navid; Thakur, Vijay Kumar; Kumar, Alan Prem; Sharifi, Esmaeel; Varma, Rajender S.; Aref, Amir Reza; Wojnilowicz, Marcin; Zarrabi, Ali; Karimi-Maleh, Hassan; Voelcker, Nicolas H.; Mostafavi, Ebrahim; Orive, Gorka (AICHE Online Library, 2022)Green chemistry has been a growing multidisciplinary field in recent years showing great promise in biomedical applications, especially for cancer therapy. Chitosan (CS) is an abundant biopolymer derived from chitin and ... -
Correction: The long and short non-coding RNAs modulating EZH2 signaling in cancer (Journal of Hematology & Oncology, (2022), 15, 1, (18), 10.1186/s13045-022-01235-1)
Mirzaei, Sepideh; Gholami, Mohammad Hossein; Hushmandi, Kiavash; Hashemi, Farid; Zabolian, Amirhossein; Canadas, Israel; Zarrabi, Ali; Nabavi, Noushin; Aref, Amir Reza; Crea, Francesco; Wang, Yuzhuo; Ashrafizadeh, Milad; Kumar, Alan Prem (BioMed Central Ltd, 2022)The original article [1] contained an error in co-author, Farid Hashemi’s name which has since been corrected. © 2022, The Author(s). -
Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: stimuli-responsive carriers, co-delivery and suppressing resistance
Ashrafizadeh, Milad; Saebfar, Hamidreza; Gholami, Mohammad Hossein; Hushmandi, Kiavash; Zabolian, Amirhossein; Zarrabi, Ali (2022)Introduction: The application of doxorubicin (DOX) in cancer therapy has been limited due to its drug resistance and poor internalization. Graphene oxide (GO) nanostructures have the capacity for DOX delivery while promoting ... -
Exosomes as promising nanostructures in diabetes mellitus: from insulin sensitivity to ameliorating diabetic complications
Diabetes mellitus (DM) is among the chronic metabolic disorders that its incidence rate has shown an increase in developed and wealthy countries due to lifestyle and obesity. The treatment of DM has always been of interest, ... -
The long and short non-coding RNAs modulating EZH2 signaling in cancer
Mirzaei, Sepideh; Gholami, Mohammad Hossein; Hushmandi, Kiavash; Hshemi, Farid; Zabolian, Amirhossein; Canadas, Israel; Zarrabi, Ali; Nabavi, Noushin; Aref, Amir Reza; Crea, Francesco; Wang, Yuzhuo; Ashrafizadeh, Milad; Kumar, Alan Prem (2022)Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in encoding proteins. However, they participate in developmental and biological processes and their abnormal expression affects cancer ... -
Long non-coding RNAs and exosomal incRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling
Entezari, Maliheh; Ghanbarirad, Maryam; Taheriazam, Afshin; Sadrkhanloo, Mehrdokht; Zabolian, Amirhossein; Shekhi Beig Goharrizi, Mohammad Ali; Hushmandi, Kiavash; Aref, Amir Reza; Ashrafizadeh, Milad; Zarrabi, Ali; Nabavi, Noushin; Rabiee, Navid; Hashemi, Mehrdad; Samarghandian, Saeed (Elsevier Science, 2022)Among the different kinds of tumors threatening human life, lung cancer is one that is commonly observed in both males and females. The aggressive behavior of lung cancer and interactions occurring in tumor microenvironment ... -
Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling
Entezari, Maliheh; Ghanbarirad, Maryam; Taheriazam, Afshin; Sadrkhanloo, Mehrdokht; Zabolian, Amirhossein; Goharrizi, Mohammad Ali Shekhi Beig; Hushmandi, Kiavash; Aref, Amir Reza; Ashrafizadeh, Milad; Zarrabi, Ali; Nabavi, Noushin; Rabiee, Navid; Hashemi, Mehrdad; Samarghandian, Saeed (Elsevier, 2022)Among the different kinds of tumors threatening human life, lung cancer is one that is commonly observed in both males and females. The aggressive behavior of lung cancer and interactions occurring in tumor microenvironment ... -
Long noncoding RNAs (lncRNAs) in pancreatic cancer progression
Ashrafizadeh, Milad; Rabiee, Navid; Prem Kumar, Alan; Sethi, Gautam; Zarrabi, Ali; Wang, Yuzhuo (Elsevier Science, 2022)Long noncoding RNAs (lncRNAs) are RNA molecules involved in gene regulation at transcriptional, post-transcriptional, and epigenetic levels. lncRNAs participate in regulating apoptosis and autophagy in pancreatic cancer ... -
Long noncoding RNAs: A novel insight in the leukemogenesis and drug resistance in acute myeloid leukemia
Kirtonia, Anuradha; Ashrafizadeh, Milad; Hushmandi, Kiavash; Zabolian, Amirhossein; Bejandi, Atefe K.; Rani, Reshma; Pandey, Amit K.; Baligar, Prakash; Kumar, Vinit; Das, Bhudev C.; Garg, Manoj (Wiley-Blackwell, 2021)Acute myeloid leukemia (AML) is a common hematological disorder with heterogeneous nature that resulted from blocked myeloid differentiation and an enhanced number of immature myeloid progenitors. During several decades, ... -
Mission impossible for cellular internalization: When porphyrin alliance with UiO-66-NH2 MOF gives the cell lines a ride
Ahmadi, Sepideh; Jajarmi, Vahid; Ashrafizadeh, Milad; Zarrabi, Ali; Haponiuk, Józef T.; Saeb, Mohammad Reza; Lima, Eder C.; Rabiee, Mohammad; Rabiee, Navid (Elsevier, 2022)Is it possible to accelerate cell internalization by hybridization of nanomaterials? Herein we support the realization of using metal-organic frameworks (MOFs) with the assistance of rigid porphyrin structure (H2TMP) aimed ... -
Molecular landscape of LncRNAs in prostate cancer: A focus on pathways and therapeutic targets for intervention
Mirzaei, Sepideh; Abad Paskeh, Mahshid Deldar; Okina, Elena; Gholami, Mohammad Hossein; Hushmandi, Kiavash; Hashemi, Mehrdad; Kalu , Azuma; Zarrabi, Ali; Nabav, Noushin; Rabiee, Navid; Sharifi, Esmaeel; Karimi-Maleh, Hassan; Ashrafizadeh, Milad; Kumar, Alan Prem; Wang, Yuzhuo (PMC, 2022)Background: One of the most malignant tumors in men is prostate cancer that is still incurable due to its heterog‑ enous and progressive natures. Genetic and epigenetic changes play signifcant roles in its development. ... -
(Nano)platforms in bladder cancer therapy: Challenges and opportunities
Ashrafizadeh, Milad; Zarrabi, Ali; Karimi-Maleh, Hassan; Taheriazam, Afshin; Mirzaei, Sepideh (John Wiley and Sons Inc, 2022)Urological cancers are among the most common malignancies around the world. In particular, bladder cancer severely threatens human health due to its aggressive and heterogeneous nature. Various therapeutic modalities have ... -
Nanotechnological approaches in prostate cancer therapy: Integration of engineering and biology
Ashrafizadeh, Milad; Aghamiri, Shahin; Tan, Shing Cheng; Zarrabi, Ali; Sharifi, Esmaeel (Elsevier B.V., 2022)Nanocarriers have received special attention in biomedicine for the treatment of various diseases, especially cancer, as one of the leading causes of death worldwide. Nanocarriers can improve the potential of contemporary ... -
Non-coding RNA-based regulation of inflammation
Ashrafizadeh, Milad; Zarrabi, Ali; Mostafavi, Ebrahim; Aref, Amir Reza; Sethi, Gautam; Wang, Lingzhi; Tergaonkar, Vinay (Elsevier Science, 2022)nflammation is a multifactorial process and various biological mechanisms and pathways participate in its development. The presence of inflammation is involved in pathogenesis of different diseases such as diabetes mellitus, ... -
Non-coding RNAs and macrophage interaction in tumor progression
Entezari, Maliheh; Sadrkhanloo, Mehrdokht; Rashidi, Mohsen; Asnaf, Sholeh Etehad; Taheriazam, Afshin; Hashemi, Mehrdad; Ashrafizadeh, Milad; Zarrabi, Ali; Rabiee, Navid; Hushmandi, Kiavash; Mirzaei, Sepideh; Sethi, Gautam (Elsevier Ireland Ltd, 2022)The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage polarization in TME to affect cancer progression. ... -
Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches
Ashrafizadeh, Milad; Delfi, Masoud; Zarrabi, Ali; Sharifi, Esmaeel; Rabiee, Navid; Paiva-Santos, Ana Cláudia; Kumar, Alan Prem; Hushmandi, Kiavash; Nazarzadeh Zare, Ehsan; Makvandi, Pooyan (Elsevier, 2022)The site-specific delivery of antitumor agents is of importance for providing effective cancer suppression. Poor bioavailability of anticancer compounds and the presence of biological barriers prevent their accumulation ... -
Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response
Ashrafizadeh, Milad; Deldar Abad Paskeh, Mahshid; Mirzaei, Sepideh; Gholami, Mohammad Hossein; Zarrabi, Ali (2022)Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent in the treatment of this malignant ... -
Wnt/β-Catenin signaling as a driver of hepatocellular carcinoma progression: an emphasis on molecular pathways
Deldar Abad Paskeh, Mahshid; Mirzaei, Sepideh; Ashrafizadeh, Milad; Zarrabi, Ali; Sethi, Gautam (Dove Medical Press, 2021)Liver cancers cause a high rate of death worldwide and hepatocellular carcinoma (HCC) is considered as the most common primary liver cancer. HCC remains a challenging disease to treat. Wnt/β-catenin signaling pathway is ...
