Browsing by Author "Bilir, Cemil"
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The anticancer potential of chlorine dioxide in small-cell lung cancer cells
Yıldız, Salih Zeki; Bilir, Cemil; Eskiler, Gamze Güney; Bilir, Filiz (CUREUS INC, 2022)Background Chlorine dioxide (ClO2) is an effective disinfectant consisting of oxygen, chloride, and potassium. Because of its high oxidative capacity, ClO2 exerts antimicrobial, antiviral, and antifungal effects. However, ... -
By 2022, cancer is now a more chronic disease with chronic difficulties to go along with It
Sumbul, Ahmet Taner; Sedef, Ali Murat; Karacin, Cengiz; Bilir, Cemil; Akagunduz, Baran (Turkiye Klinikleri, 2022)Cancer is a disease in which some body cells with genetic or epigenetic changes become capable of replicating and invading other regions of the body uncontrollably. Numerous functional abilities and features are acquired ... -
By 2022, cancer is now a nore chronic disease with chronic difficulties to go along with It
Sümbül, Ahmet Taner; Sedef, Ali Murat; Karaçin, Cengiz; Bilir, Cemil; Akagündüz, Baran (Turkiye Klinikleri, 2022)Cancer is a disease in which some body cells with genetic or epigenetic changes become capable of replicating and invading other regions of the body uncontrollably. Numerous functional abilities and features are acquired ... -
The efficacy of indoximod upon stimulation with pro-inflammatory cytokines in triple-negative breast cancer cells
Guney Eskiler, Gamze; Bilir, Cemil (Taylor & Francis Online, 2021)Background: Indoleamine 2,3-dioxygenase (IDO) inhibition has received much attention in cancer immunotherapy due to its role in immune escape in cancer cells. Additionally, changes in the pro-inflammatory cytokine levels ... -
Mechanisms of abemaciclib, a CDK4/6 inhibitor, induced apoptotic cell death in prostate cancer cells in vitro
Guney Eskiler, Gamze; Deveci Ozkan, Asuman; Haciefendi, Ayten; Bilir, Cemil (Elsevier, 2022)The therapeutic effects of abemaciclib (ABE), an inhibitor of cyclin- dependent kinases (CDK) 4/6, on the proliferation of two types of prostate cancer (PC) cells were revealed. In this study, in vitro cytotoxic and apoptotic ... -
The prognostic and predictive values of differential expression of exosomal receptor tyrosine kinases and associated with the PI3K/AKT/mTOR signaling in breast cancer patients undergoing neoadjuvant chemotherapy
Guney Eskiler, Gamze; Kazan, Nur; Haciefendi, Ayten; Deveci Ozkan, Asuman; Ozdemir, Kayhan; Ozen, Mirac; Kocer, Havva Belma; Yilmaz, Fahri; Kaleli, Suleyman; Sahin, Elvan; Bilir, Cemil (Springer Science and Business Media Deutschland GmbH, 2022)Purpose: Cancer cell-derived exosomes are the mediator of the tumor microenvironment and the molecular content of exosomes presents a promising prognostic or predictive marker in tumor progression and the treatment response ...