Browsing by Author "Bozkurt, Ceyhun"
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Are the anxiety levels of pediatric hematology-oncology patients different from healthy peers during the COVID-19 outbreak?
Cakiroglu, Suleyman; Yeltekin, Ceren; Fisgin, Tunc; Oner, Ozlem B; Adakli Aksoy, Basak; Bozkurt, Ceyhun (2020)The COVID-19 outbreak has caused anxiety among children with hematology-oncology disease and their families, as it has in every segment of society. In this study, we aimed to detect the anxiety levels of children with ... -
Assessment of serum vitamin D in pediatric hematopoietic stem cell transplantation patients and its relation with complications
Karakaş, Zeynep; Aydoğdu, Selime; Yılmaz, Yasin; Bozkurt, Ceyhun; Aykanat, Alper; Fışgın, Tunç (Nature Publishing Group, 2018)Recently, evaluation of serum vitamin D level in pediatric hematopoietic stem cell transplantation (HSCT) patients gained popularity, as there is close relation with development of GVHD and complications. Our aim was ... -
Beta globin mutations in Turkish, northern Iraqi and albanian patients with beta thalassemia major
Hançer, Veysel Sabri; Fışgın, Tunç; Büyükdoğan, Murat; Bozkurt, Ceyhun; Lako, Sotiraq (Pagepress Publ, 2018)The mutation detection of beta thalassemia is absolutely necessary for molecular diagnosis, as well as any genetic epidemiological study. The b globin gene has 3 exons and 2 introns, involved in beta-thalassemic pathogenesis. ... -
Biallelic form of a known CD3E mutation in a patient with severe combined immunodeficiency
Erman, Baran; Fırtına, Sinem; Fışgın, Tunç; Bozkurt, Ceyhun; Erol Cipe, Funda (Springer/Plenum Publishers, 2020)T cell receptor (TCR) complex consists of αβ or γδ TCR chains in combination with four CD3 subunits, CD3ε, CD3γ, CD3δ, and CDζ [1]. This complex is required for thymocyte development and the initiation of T cell-mediated ... -
CMV-specific T-Cells for Treatment of CMV infection after hematopoietic stem cell transplantation in a pediatric case: First application in Turkey
Celilova, Sevil; Töret, Ersin; Adaklı Aksoy, Başak; Ovalı, Ercüment; Bozkurt, Ceyhun (Galenos Yayincilik, 2020)Cytomegalovirus (CMV) infection is still a major complication after allogeneic hematopoietic stem cell transplantation (HSCT) [1,2]. Unfortunately, prolonged antiviral treatment of CMV infection causes a delayed ... -
Comparison of allogeneic stem cell transplantation results from related or unrelated donors in beta-thalassemia major
Aydoğdu, Selime; Mergen, Azize; Adaklı Aksoy, Başak; Çokluk, Mila N.; Dikme, Gürcan; Erol Cipe, Funda; Fışgın, Tunç; Bozkurt, Ceyhun (Nature Publishing Group, 2019)Although there have been significant improvements with conventional therapies in beta thalassemia major, hematopoietic stem cell transplantation is only curative therapy. Related donors are preferred to diminish ... -
Comparison of hematopoietic stem cell transplantation results in patients with β-thalassemia major from three different graft types
Aydoğdu, Selime; Töret, Ersin; Adaklı Aksoy, Başak; Aydın, Muhammed Fatih; Erol Cipe, Funda; Bozkurt, Ceyhun; Fışgın, Tunç (Taylor & Francis Online, 2021)Allogeneic hematopoietic stem cell transplantation (HSCT) is the curative therapy for β-thalassemias that induces severe life-threatening complications. The human leukocyte antigen (HLA) registries and umbilical cord blood ... -
Comparison of turkish stem cell coordination center (TURKOK) with Istanbul university bone marrow bank (TRIS); A single center experience in match unrelated donors
Mergen, Azize; Aydoğdu, Selime; Adaklı Aksoy, Başak; Savcı, Yunus Emre; Dikme, Gürcan; Erol Cipe, Funda; Bozkurt, Ceyhun; Fışgın, Tunç (Nature Publishing Group, 2019)Match family donors are the preferable options in allogenic stem cell transplant. However, in the absence of donor relatives match unrelated donors have been an option. In this study, the donor screening, transplant ... -
Could the COVID-19 infection have a better prognosis than expected in pediatric hematology oncology and bone marrow transplant patients?
Öner, Özlem Başoğlu; Aksoy, Başak Adaklı; Yaman, Ayhan; Sütçü, Murat; Cipe, Funda; Atça, Ali Önder; Bozkurt, Ceyhun; Fışgın, Tunç (AVES, 2021)Coronavirus disease 2019 (COVID-19) is a pandemic that spread rapidly worldwide (1). So far, very few reports concerning the impact of COVID-19 among patients with pediatric hematologic-oncologic diseases are available ... -
Cross-sectional study: long term follow-up care for pediatric cancer survivors in a developing country, Turkey: current status, challenges, and future perspectives
İncesoy Özdemir, Sonay; Taçyıldız, Nurdan; Varan, Ali; Kebudi, Rejin; Zülfikar, Osman Bülent; Celkan, Tülin Tiraje; Şahin, Gürses; Çorapçıoğlu, Funda Vesile; Keskin Yıldırım, Zuhal; Pınarlı, Faruk Güçlü; Olgun, Hatice Nur; Sarı, Neriman; Dağdemir, Ayhan; Özyörük, Derya; Eren, Tuba; Çakır, Fatma Betül; Adaklı Aksoy, Başak; Bozkurt, Ceyhun; Güler, Elif; Özgüven, Ali Aykan; Erbey, Mehmet Fatih; Berber Hamamcı, Melda; Dinçaslan, Handan; Ünal, Emel; Kantar, Mehmet (Scientific and Technical Research Council of Turkey, 2020)Aim: The main purpose of this study is to determine the current status of long-term follow-up (LTFU) for childhood cancer survivors and the challenges of LTFU for pediatric cancer survivors at pediatric oncology institutions ... -
Different kinetics and risk factors for isolated extramedullary relapse after allogeneic hematopoietic stem cell transplantation in children with acute leukemia
Hazar, Volkan; Öztürk, Gülyüz; Yalçın, Koray; Uygun, Vedat; Aksoylar, Serap; Bozkurt, Ceyhun (Elsevier, 2021)Relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the most frequent cause of posttransplant mortality. Isolated extramedullary relapse (iEMR) after HSCT is relatively rare ... -
Donor lymphocyte infusion administrations after allogeneic stem cell transplantations in pediatrics: a single center experience
Aydoğdu, Selime; Mergen, Azize; Adaklı Aksoy, Başak; Akbay, Hazal S.; Erol Cipe, Funda; Dikme, Gürcan; Fışgın, Tunç; Bozkurt, Ceyhun (Nature Publishing Group, 2019)Loss of chimerism is one of the major problems after allogeneic stem cell transplantation(SCT). Donor- lymphocyte infusions(DLI) are used as a treatment after taper or stopping immunosuppression. In this study, DLI ... -
Economic and psychosocial problems experienced by pediatric with cancer patients and their families during the treatment and follow-up process
Bozkurt, Ceyhun; Uğurlu, Zilan; Tanyıldız, Hikmet Gülşah; Yeşil, Şule; Kiraz, Haşim; Toprak, Şule; Yüksek, Nazmiye; Şahin, Gürses; Ertem, Ulya (Turkish Pediatrics Assoc, 2019)Amaç: Dr. Sami Ulus Kadın Doğum ve Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi Çocuk Onkoloji Kliniği’nde tedavi edilmiş kanserli çocuk hastaların ve yakınlarının bu süreçte karşılaştıkları psikososyal ve ... -
Evaluation of the risk factors for BK virus-associated hemorrhagic cystitis in pediatric bone marrow transplantation patients: Does post-transplantation cyclophosphamide increase the frequency?
Zengin Ersoy, Gizem; Bozkurt, Ceyhun; Adaklı Aksoy, Başak; Başoğlu Öner, Özlem; Aydoğdu, Selime; Çipe, Funda; Sütçü, Murat; Özkaya, Ozan; Tunç, Fışgın (Wiley, 2022)Background: BKV-HC is one of the most significant complications of HSCT. This ret -rospective study aimed to determine the frequency of BKV-HC in pediatric patients undergoing HSCT, detect the ... -
Extracorporeal photopheresis treatment for steroid resistant graft versus host disease in pediatrics: single center experience
Aksoy, Başak Adaklı; Savcı, Yunus Emre; Mergen, Azize; Aydoğdu, Selime; Dikme, Gürcan; Bozkurt, Ceyhun; Fışgın, Tunç (Nature Publishing Group, 2019)Background: Steroid resistant graft vs host disease (GVHD) is defined as unresolved or worsened symptomatology of GVHD at day 14 despite effective immunosuppression with steroid therapy. Second line immunosuppressive agents, ... -
Hit three birds with one stone: successful stem cell transplantation from one family donor to three siblings
Aksoy, Başak Adaklı; Aydoğdu, Selime; Dikme, Gürcan; Mergen, Azize; Bozkurt, Ceyhun; Fışgın, Tunç (Nature Publishing Group, 2019)Background: Thalassemia major is a single gene related hereditary hemoglobinopaty required life long regular transfusions with chelation therapies. Stem cell transplantation is the only curative treatment of the disease. ... -
Invasive saprochaete capitata Infection in a patient with autosomal recessive CARD9 deficiency and a review of the literature
Erman, Baran; Fırtına, Sinem; Aksoy, Başak Adaklı; Aydoğdu, Selime; Genç, Gonca Erköse; Doğan, Öner; Bozkurt, Ceyhun; Fışgın, Tunç; Erol Cipe, Funda (Springer/Plenum Publishers, 2020)Purpose Autosomal recessive (AR) CARD9 deficiency is an inherited immune disorder which results in impaired innate immunity against various fungi. Superficial and invasive fungal infections, mainly caused by Candida or ... -
A novel candidate gene for predisposition of hodgkin lymphoma; Pregnan x receptor (PXR)
Kebudi, Rejin; Erbilgin, Yucel; Khodzhaev, Khusan; Saritas, Merve; Bozkurt, Ceyhun; Sayitoglu, Muge (AMER SOC HEMATOLOGY, 2021)No Abstract Available -
Primary immunodeficiencies: HSCT experiences of a single center in Turkey
Erol Cipe, Funda; Adaklı Aksoy, Başak; Aydoğdu, Selime; Dikme, Gürcan; Kıykım, Ayca; Aydoğmus, Çiğdem; Yücel, Esra; Bozkurt, Ceyhun; Fışgın, Tunç (WILEY, 2021)Background Primary immunodeficiency diseases (PID) are characterized by the occurrence of frequent infections and are caused by many genetic defects. Hematopoietic stem cell transplantation (HSCT) is the only curative ... -
Prognostic factors for survival in children who relapsed after allogeneic hematopoietic stem cell transplantation for acute leukemia
Hazar, Volkan; Tezcan Karasu, Gülsün; Öztürk, Gülyüz; Küpesiz, Alphan; Aksoylar, Serap; Özbek, Namık; Uygun, Vedat; İleri, Talia; Okur, Fatma Visal; Koçak, Ülker; Çakı Kılıç, Suar; Akçay, Arzu; Güler, Elif; Kansoy, Savaş; Karakükcü, Musa; Bayram, İbrahim; Aksu , Tekin; Yeşilipek, Akif; Karagün, Barbaros Şahin; Yılmaz, Şebnem; Ertem, Mehmet; Uçkan, Duygu; Fışgın, Tunç; Gürsel, Orhan; Yaman, Yöntem; Bozkurt, Ceyhun; Gökçe, Müge (2020)Background: Post-transplant relapse has a dismal prognosis in children with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Data on risk factors, treatment options, and outcomes ...
