Browsing by Author "Bulut, Huri"
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Angiotensin IV improves spatial memory in streptozotocin‑induced diabetic rats by reducing oxidative stress and altering BDNF levels
Kilic, Aysu; Ustunova, Savas; Elibol, Birsen; Bulut, Huri; Meral, Ismail; Sahin, Gulderen (NCI CPTAC, 2021)In this study, we investigated the protective effects of angiotensin IV (Ang IV) on cognitive function in streptozotocin (STZ)‑induced diabetic rats. Male Wistar albino rats, were randomly divided into four groups; control ... -
Assessment of oxidative stress effects in serum determined by FT-IR spectroscopy in cholangiocarcinoma patients
Bulut, Huri; Tarhan, Nevzat; Buyuk, Melek; Serin, Kurşat Rahmi; Ulukaya, Engin; Depciuch, Joanna; Parlinska-Wojtan, Magdalena; Guleken, Zozan (AMG Transcend Association, 2023)Cholangiocarcinoma (CCA) is a heterogeneous malignant tumor containing intrahepatic and extrahepatic bile ducts and gallbladder carcinoma. Mostly diagnosed at an advanced stage with a <5% cure chance. Early-stage diagnosis ... -
Assessment of structural protein expression by FTIR and biochemical assays as biomarkers of metabolites response in gastric and colon cancer
Guleken, Zozan; Bulut, Huri; Gültekin, Güldal İnal; Arikan, Soykan; Yaylim, Ilhan; Hakan, Mehmet Tolgahan; Sönmez, Dilara; Tarhan, Nevzat K.; Depciuch, Joanna (Elsevier B.V., 2021)Colon and gastric cancers are the widespread benign types of cancers which are synchronous and metachronous neoplasms. In terms of the progression and progress of the disease, metabolic processes and differentiation in ... -
Assessment of the effect of endocrine abnormalities on biomacromolecules and lipids by FT-IR and biochemical assays as biomarker of metabolites in early Polycystic ovary syndrome women
Guleken, Zozan; Bulut, Huri; Bulut, Berk; Depciuch, Joanna (Elsevier, 2021)Polycystic ovary syndrome (PCOS) is a common endocrinopathy associated with metabolic disturbances.Both in the development and improvement of the disease, the structure of phospholipids and proteinsin the blood serum plays ... -
Blood serum lipid profiling may improve the management of recurrent miscarriage: a combination of machine learning of mid-infrared spectra and biochemical assays
Guleken, Zozan; Bahat, Pinar Yalcin; Toto, Omer Faruk; Bulut, Huri; Jakubczyk, Pawel; Cebulski, Jozef; Paja, Wieslaw; Pancerz, Krzysztof; Wosiak, Agnieszka; Depciuch, Joanna (SPRINGER HEIDELBERG, 2022)The present article is focused on developing and validating an efficient, credible, minimally invasive technique based on spectral signatures of blood samples of women with recurrent miscarriage vs. those of healthy ... -
Characterization of Covid-19 infected pregnant women sera using laboratory indexes, vibrational spectroscopy, and machine learning classifications
Guleken, Zozan; Jakubczyk, Paweł; Paja, W.; Krzysztof, Pancerz; Bulut, Huri; Öten, Esra; Depciuch, Joanna; Tarhan, Nevzat K. (Elsevier B.V., 2022)Herein, we show differences in blood serum of asymptomatic and symptomatic pregnant women infected with COVID-19 and correlate them with laboratory indexes, ATR FTIR and multivariate machine learning methods. We collected ... -
Conserved amino acid residues that affect structural stability of candida boidinii formate dehydrogenase
Bulut, Huri; Yuksel, Busra; Gul, Mehmet; Eren, Meryem; Karatas, Ersin; Kara, Nazli; Yilmazer, Berin; Kocyigit, Abdurrahim; Labrou, Nikolaos E.; Bi̇nay, Barıs Is (Springer, 2021)The NAD+-dependent formate dehydrogenase (FDH; EC 1.2.1.2) from Candida boidinii (CboFDH) has been extensively used in NAD(H)-dependent industrial biocatalysis as well as in the production of renewable fuels and chemicals ... -
Correction: Serum Vasostatin-1 level is increased in women with preeclampsia
Hamzaoglu, Kubra; Bulut, Huri; Malik, Eduard; Guralp, Onur; Tuten, Abdullah; Tuten, Nevin; Gok, Koray (Georg Thieme Verlag Stuttgard, 2022)No Abstract Available -
Correlation between endometriomas volume and Raman spectra. Attempting to use Raman spectroscopy in the diagnosis of endometrioma
Guleken, Z.; Bulut, H.; Bulut, B.; Paja, W.; Parlinska-Wojtan, M.; Depciuch, J. (Elsevier B.V., 2022)The formation of the uterus lining, i.e. the endometrium, outside the uterus (ex. in the abdominal cavity, ovaries, or anywhere in the body) is called endometriosis. The presence of endometrial tissue present in the ovaries, ... -
Cuscuta campestris tedavisi ile mide kanseri hücrelerinde apoptozun indüklenmesi ve reaktif oksijen türlerinin oluşumu yoluyla proliferasyonun engellenmesi
Bulut, Huri; Durmus, Ezgi; Hacıosmanoglu, Ebru; Bozali, Kubra; Senturk, Hilal; Kocyigit, Abdurrahim (DergiPark, 2021)Amaç: Kanser tahrip edici, ölümcül bir hastalıktır ve dünya çapındaki ölüm nedenleri arasında ikinci sırada yer almaktadır. Mide kanseri gibi kanser türleri için farklı tedavi yöntemleri mevcut olsa da çoğu tedavi yöntemleri ... -
Diagnosis of endometriosis using endometrioma volume and vibrational spectroscopy with multivariate methods as a noninvasive method
Guleken, Zozan; Bulut, Huri; Depciuch, Joanna; Tarhan, Nevzat (Elsevier Science, 2022)Endometriomas are typically an advanced form of endometriosis that leads to the formation of scar tissue, adhesions, and an inflammatory reaction. There is no certain serum marker for the diagnosis of endometriosis. This ... -
Differential of cholangiocarcinoma disease using Raman spectroscopy combined with multivariate analysis
Depciuch, Joanna; Parlinska-Wojtan, Magdalena; Serin, Kursat Rahmi; Bulut, Huri; Ulukaya, Engin; Tarhan, Nevzat; Guleken, Zozan (2022)Cholangiocarcinoma (CCA) is a type of cancer, which 5-year survival is lower than 20 %, and which is detected mostly in advanced stage of the disease. Unfortunately, there are no diagnostic tools, which could show changes ... -
Effect of metal Ions on the activity of ten NAD-dependent formate dehydrogenases
NAD-dependent formate dehydrogenase (FDH) enzymes are frequently used in industrial and scientific applications. FDH is a reversible enzyme that reduces the NAD molecule to NADH and produces CO2 by oxidation of the formate ... -
The effect of omentectomy on the blood levels of adipokines in obese patients with endometrial cancer
Comba, Cihan; Ozdemir, Isa Aykut; Demirayak, Gokhan; Erdogan, Sakir Volkan; Demir, Omer; Ozlem Yildiz, Gunes; Bulut, Huri; Karakas, Sema; Gulseren, Varol; Afsar, Selim; Gungorduk, Kemal (Elsevier Science, 2022)Objective To investigate the blood levels of adipokines in obese patients with endometrial cancer who have and have not undergone omentectomy. Methods Between September 2017 and September 2019, the study recruited 54 ... -
Effects of combined administration of doxorubicin and chloroquine on lung pathology in mice with solid Ehrlich ascites carcinoma
Utkusavas, Ayfer; Gurel Gurevin, Ebru; Yilmazer, Nadim; Uvez, Ayca; Oztay, Fusun; Bulut, Huri (2022)Combined use of a chemotherapeutic agent and an autophagy inhibitor is a novel cancer treatment strategy. We investigated the effects of chloroquine (CQ) on lung pathology caused by both solid Ehrlich ascites carcinoma ... -
Effects of TNF inhibitors and an IL12/23 inhibitor on changes in body weight and adipokine levels in psoriasis patients: a 48-week comparative study
Onsun, Nahide; Akaslan, Tahsin Cagdas; Sallahoglu, Kadriye; Gulcan, Aliye Sevdem; Bulut, Huri; Yabaci, Aysegul (Taylor and Francis, 2021)Background: Psoriasis is a chronic inflammatory disease associated with obesity and metabolic syndrome. Adipokines are thought to be a link between psoriasis and obesity. Leptin, adiponectin, and omentin are bioactive ... -
The healing effects of the topical mesenchymal stem cell application on colonic anastomosis subjected to ischemia reperfusion injury
Ozden, Huseyin; Karaca, Gokhan; Bulut, Huri; Niyaz, Mehmet; Gomec, Muhammed; Daphan, Cagatay E. (KAFKAS UNIV, 2021)Intestinal ischemia reperfusion injury (IRI) is a challenging problem and it adversely affects the healing of colonic anastomosis. Our experimental study aimed to investigate the role of mesenchymal stem cells (MSC) ... -
Hydrogen sulphide and nitric oxide cooperate in cardioprotection against ischemia/reperfusion injury in isolated rat heart
Ustunova, Savas; Takir, Selcuk; Yilmazer, Nadim; Bulut, Huri; Altindirek, Didem; Ng, Ozden Hatirnaz; Tansel, Cihan Demirci; Dogan, Birsel Sonmez Uydes; Ozbek, Ugur; Ilkay Armutak, Elif; Gurevin, Ebru Gurel (NLM (Medline), 2020)BACKGROUND/AIM: This study was designed to provide further evidence for the interactions between hydrogen sulfide (H2S) and nitric oxide (NO) in ischemia/reperfusion (I/R) injury. MATERIALS AND METHODS: Rat hearts were ... -
Identification of polycystic ovary syndrome from blood serum using hormone levels via Raman spectroscopy and multivariate analysis
Guleken, Z.; Bulut, H.; Bulut, B.; Paja, W.; Orzechowska, B.; Parlinska-Wojtan, M.; Depciuch, J. (Elsevier, 2022)Polycystic ovarian syndrome (PCOS) is a disease, which causes infertility in women. The factors for the development of the disease are still not well understood and diagnostic methods need to be improved. Therefore, in ... -
Impaired memory by hippocampal oxidative stress in rats exposed to 900 MHz electromagnetic fields is ameliorated by thymoquinone
Ustunova, S.; Kilic, A.; Bulut, H.; Gurel-Gurevin, E.; Eris, A.H.; Meral, I. (Taylor and Francis Ltd., 2022)The protective effects of thymoquinone on learning and memory abilities and on hippocampal oxidative stress in rats exposed to 900 MHz electromagnetic field radiation at s strength of 6.0 ± 0.5 V/m for 1 h on each of 15 ...