Browsing by Author "Buyuk, Ayse Seyma"
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It is time to revitalize the Antibiotic Pipeline: Systems ecology can help
Sardas, Semra; Buyuk, Ayse Seyma; Beceren, Ayfer (Mary Ann Liebert, Inc, 2020)Antimicrobials have been known for millennia, but innovative antibiotics are currently in short supply. New antimicrobial discoveries are being threatened by planetary scale loss of biodiversity that has important impacts ... -
The long view on COVID-19 theranostics and oral antivirals: living with endemic disease and lessons from molnupiravir
Al-Taie, Anmar; Denkdemir, Fatma Rana; Buyuk, Ayse Seyma; Sardas, Semra (Atypon, 2022)The long view on living with COVID-19 as an endemic disease calls for expanding the planetary health inter-vention toolbox. We will need a battery of vaccines, small molecule oral antiviral drugs, and biomarkers toforecast ... -
Preparation and evaluation of inflammation targeted nano-micellar formulation of celecoxib
Bahadori, Fatemeh; Buyuk, Ayse Seyma; Kozanoglu, Ahmed Serdar; Eskandari, Zahra; Ankarali, Handan; Kepekci Tekkeli, Serife Evrim; Kocyigit, Abdurrahim (Bezmialem Vakif Univ, 2019)Objective: Celecoxib (CLX), brand named Celebrex, which belongs to non-steroidal anti-inflammatory drugs family, selectively inhibits the cytokine related cyclooxygenase-2 isoenzyme and thus, possesses less gastrointestinal ... -
A scoping systematic assessment for post-marketing abuse drug withdrawal
Al-Taie, Anmar; Buyuk, Ayse Seyma; Sardas, Semra (OXFORD UNIV PRESS, 2022)Objectives The aim of this study was to identify the post-marketing withdrawal of medicines due to their adverse drug reactions (ADRs)-related abuse effects and to examine the types of evidence, mechanisms and patterns for ...