Browsing by Author "Darici, Hakan"
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Cytotoxic effects of n-(4-chlorophenyl)-1h-ındole-2-carboxamide on bone cancer cells
INTRODUCTION:Osteosarcoma is a common tumor of high malignancy, usually derived from mesenchymal tissues. The lack of response to chemotherapeutic treatments indicates the importance of investigating new therapeutic methods. ... -
GFP geni aktarılmış mezenkimal kök hücre davranışlarının 4 boyutlu kültürde yapay zeka kullanılarak analizi
Ozdemir, Ceren (İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2021)Hücrelerin moleküler mekanizmalarını ve davranışlarını incelemek için kullanılan iki boyutlu (2B) konvansiyonel hücre kültür sistemleri ucuz ve kolay uygulanabilir olmasına karşın hücrelerin vücut içindeki 3 boyutlu (3B) ... -
Mesenchymal stem cells for the treatment of covid-19: why and when they should be used?
Darici, Hakan; Sun, Eda; Irmak, Duygu Koyuncu; Karaöz, Erdal (Nova Science Publishers, 2020)COVID-19 is a pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which caused deaths of more than 300.000 people around the world within the first few months of 2020. SARS-CoV-2 uses ACE2 ... -
Mesenchymal stem cells for the treatment of covid-19: why and when they should be used?
Darici, Hakan; Sun Gungorurle, Eda; Koyuncu Irmak, Duygu; Karaoz, Erdal (Nova Science Publishers, 2021)COVID-19 is a pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which caused deaths of more than 300.000 people around the world within the first few months of 2020. SARS-CoV-2 uses ACE2 ... -
Mezenkimal kök hücrelerde sferoid oluşumunu tetikleyecek yeni bir üç boyutlu kültür materyali geliştirilmesi
Nurseval Oyunlu, Aslı (İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2022)Hücrelerdeki fizyolojik aktiviteleri, davranışları ve gelişimleri incelemek için uygulanabilirliği kolay ve maliyeti düşük olan iki boyutlu (2B) hücre kültür yöntemleri kullanılmaktadır. Ancak 2B kültürün hücre ve dokuların ... -
Olfactory ensheathing cells: unique glial cells promising for treatments of spinal cord injury
Ursavas, Selin; Darici, Hakan; Karaoz, Erdal (Wiley, 2021)Spinal cord injury (SCI) is generally the consequence of physical damage, which may result in devastating consequences such as paraplegia or paralysis. Some certain candidates for SCI repair are olfactory ensheathing cells ... -
Preparation and characterization of graphene-based 3D biohybrid hydrogel bioink for peripheral neuroengineering
Zorba Yildiz, Asli Pinar; Darici, Hakan; Yavuz, Burcak; Abamor, Emrah Sefik; Ozdemir, Ceren; Yasin, Muge Elif; Bagirova, Melahat; Allahverdiyev, Adil; Karaoz, Erdal (Jove, 2022)Peripheral neuropathies can occur as a result of axonal damage, and occasionally due to demyelinating diseases. Peripheral nerve damage is a global problem that occurs in 1.5%-5% of emergency patients and may lead to ... -
Stem cell based therapy option in COVID-19: is it really promising?
Koyuncu Irmak, Duygu; Darici, Hakan; Karaoz, Erdal (INT SOC AGING & DISEASE, 2020)The COVID-19 patients were first detected in China, in December 2019, then the novel virus with associated pneumonia and other diseases spread quickly to worldwide becoming a serious public health intimidation. Despite all ... -
Synthesis, FT-IR and NMR characterization, antimicrobial activity, cytotoxicity and DNA docking analysis of a new anthraquinone derivate compound
Celik, Sefa; Ozkok, Funda; Ozel, Aysen E.; Sahin, Yesim Muge; Akyuz, Sevim; Sigirci, Belgi Diren; Kahraman, Beren Basaran; Darici, Hakan; Karaoz, Erdal (Taylor & Francis Inc, 2020)A new anthraquinone [1-(2-Aminoethyl)piperazinyl-9,10-dioxo-anthraquinone] derivative was synthesized and characterized by density functional theory (DFT) calculations, experimental and theoretical vibrational spectroscopy ... -
Wound treatment by stem cells
Sener, Leyla Turker; Darici, Hakan; Albeniz, Isil; Karaoz, Erdal (SPRINGER INTERNATIONAL PUBLISHING AG, 2017)*
