Browsing by Author "Dere, E."
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Effects of novel targeted anticancer drugs on cytotoxicity, apoptosis, angiogenesis, EMT, drug resistance and autophagic mechanism
Aydinlik, S.; Uvez, A.; Armutak, E. I.; Dere, E.; Ulukaya, Engin (Oxford Univ Press, 2019)Background: Metastatic coloncancer has asurvival rate less than %5 despite the use of effective chemotherapeutic regimen. Prognosticand predictiveimportance of EGFR is still contradictivein coloncancer. Tyrosine kinase ... -
Identification of microenvironmental regulation and therapeutic targeting of oncogenic eEF2K in pancreatic cancer
Karakas Zeybek, Didem; Kahraman, N.; Bayraktar, R.; Kabil, N.; Ulukaya, Engin; Dere, E.; Berestein, G. L.; Ozpolat, B. (Wiley, 2019)Eukaryotic elongation factor 2 kinase (eEF2K) is overexpressed in cancer cells and its overexpression is correlated with poor prognosis in several types of cancer. It has been known that pancreatic cancer (PaCa) has a ...