Browsing by Author "Erkisa, Merve"
Now showing items 1-7 of 7
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Combination of histone deacetylase inhibitor with Cu(II) 5,5- diethylbarbiturate complex induces apoptosis in breast cancer stem cells: a promising novel approach
Background: Cancer stem cells (CSC) are subpopulation within the tumor that acts a part in the initiation, progression, recurrence, resistance to drugs and metastasis of cancer. It is well known that epigenetic changes ... -
Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line
Aydinlik, Seyma; Erkisa, Merve; Cevatemre, Buse; Sarimahmut, Mehmet; Dere, Egemen; Ari, Ferda; Ulukaya, Engin (Elsevier Science Bv, 2017)Background: The outcome of triple negative breast cancer is still poor and requires improvement with better therapy options. Autophagy has recently been shown to play a role in anticancer drug resistance. Therefore, we ... -
Folic acid-conjugated cationic Ag2S quantum dots for optical imaging and selective doxorubicin delivery to HeLa cells
Duman, Fatma Demir; Erkisa, Merve; Khodadust, Rouhullah; Ari, Ferda; Ulukaya, Engin; Acar, Havva Yagci (Future Medicine Ltd, 2017)We aim to develop folic acid ( FA)-conjugated cationic Ag2S near-infrared quantum dots (NIRQDs) for the delivery of doxorubicin (DOX) selectively to folate receptor (FR)-positive cancer cells to achieve enhanced drug ... -
Natural products as a promising therapeutic strategy to target cancer stem cells
Erkisa, Merve; Sariman, Melda; Gonul Geyik, Oyku; Geyik, Caner; Stanojkovic, Tatjana; Ulukaya, Engin (2021)Cancer is still a deadly disease, and its treatment desperately needs to be managed in a very sophisticated way through fast-developing novel strategies. Most of the cancer cases eventually develop into recurrencies, for ... -
Nonapoptotic cell death induced by Hypericum species on cancer cells
Objectives. There are approximately 400 Hypericum species that grow naturally in different geographic originsof the world. Those species have been used in different folk medicines and screened for their biological ... -
Novel 1-(7-ethoxy-1-benzofuran-2-yl) substituted chalcone derivatives: synthesis, characterization and anticancer activity
Coskun, Demet; Erkisa, Merve; Ulukaya, Engin; Coskun, Mehmet Fatih; Ari, Ferda (Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)Cancer treatment still requires new compounds to be discovered. Chalcone and its derivatives exhibit anticancer potential in different cancer cells. A new series of benzofuran substituted chalcone derivatives was synthesized ... -
Preparation and characterization of palladium derivate-loaded micelle formulation in vitro as an innovative therapy option against non-small cell lung cancer cells
Erkisa, Merve; Ari, Ferda; Buyukkoroglu, Gulay; Senel, Bedriye; Yilmaz, Veysel Turan; Ulukaya, Engin (WILEY, 2021)Nanoparticles have been used in cancer treatments to target tumor and reduce side effects. In this study, we aimed to increase the effectiveness of palladium(II) complex [PdCl(terpy)](sac)·2H2O, which previously showed ...
