Browsing by Author "Erturk, Aybige"
Now showing items 1-4 of 4
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Antivirals and the potential benefits of orally Inhaled Drug Administration in COVID-19 Treatment
Sahin, Gokben; Akbal-Dagistan, Ozlem; Culha, Meltem; Erturk, Aybige; Basarir, Nur Sena; Yildiz-Pekoz, Ayca (Elsevier Science, 2022)Coronavirus Disease 2019 (COVID-19) pandemic has been on the agenda of humanity for more than 2 years. In the meantime, the pandemic has caused economic shutdowns, halt of daily lives and global mobility, overcrowding ... -
Early effects of low molecular weight heparin therapy with soft-mist inhaler for COVID-19-induced hypoxemia: a phase iib trial
Erelel, Mustafa; Kaskal, Mert; Akbal-Dagistan, Ozlem; İssever, Halim; Erturk, Aybige (MDPI, 2021)In COVID-19-induced acute respiratory distress syndrome, the lungs are incapable of filling with sufficient air, leading to hypoxemia that results in high mortality among hospitalized patients. In clinical trials, ... -
Pulmonary delivery of favipiravir in rats reaches high local concentrations without causing oxidative lung injury or sSystemic side effects
Akbal Dagistan, Ozlem; Sevim, Mustafa; Sen, Leyla Semiha; Basarir, Nur Sena; Culha, Meltem; Erturk, Aybige; Fael, Hanan; Kaptan, Engin; Sancar, Serap; Mulazimoglu Durmusoglu, Lutfiye; Yegen, Berrak C; Yildiz Pekoz, Ayca (MDPI, 2022)Favipiravir displays a rapid viral clearance, a high recovery rate and broad therapeutic safety; however, its oral administration was associated with systemic side effects in susceptible patients. Considering that the ... -
Pulmonary delivery of favipiravir inhalation solution for COVID-19 treatment: in vitro characterization, stability, in vitro cytotoxicity, and antiviral activity using real time cell analysis
Yildiz Pekoz, Ayca; Akbal Dagistan, Ozlem; Fael, Hanan; Culha, Meltem; Erturk, Aybige (TAYLOR & FRANCIS, 2022)Favipiravir, an RNA-dependent RNA polymerase (RdRp) inhibitor, is used to treat patients infected with influenza virus and most recently with SARS-CoV-2. However, poor accumulation of favipiravir in lung tissue following ...
