Browsing by Author "Güney Eskiler, Gamze"

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Mechanisms of abemaciclib, a CDK4/6 inhibitor, induced apoptotic cell death in prostate cancer cells in vitro

Güney Eskiler, Gamze; Deveci Özkan, Asuman; Hacıefendi, Ayten; Bilir, Cemil (Elsevier, 2022)

The therapeutic effects of abemaciclib (ABE), an inhibitor of cyclin- dependent kinases (CDK) 4/6, on the proliferation of two types of prostate cancer (PC) cells were revealed. In this study, in vitro cytotoxic and apoptotic ...
The prognostic and predictive values of differential expression of exosomal receptor tyrosine kinases and associated with the PI3K/AKT/mTOR signaling in breast cancer patients undergoing neoadjuvant chemotherapy

Güney Eskiler, Gamze; Kazan, Nur; Hacıefendi, Ayten; Deveci Özkan, Asuman; Özdemir, Kayhan; Özen, Miraç; Koçer, Havva Belma; Yılmaz, Fahri; Kaleli, Süleyman; Şahin, Elvan; Bilir, Cemil (Springer Science and Business Media Deutschland GmbH, 2022)

Purpose: Cancer cell-derived exosomes are the mediator of the tumor microenvironment and the molecular content of exosomes presents a promising prognostic or predictive marker in tumor progression and the treatment response ...