Browsing by Author "Gokmen, Zeliha"

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A novel 1,4-naphthoquinone-derived compound induces apoptotic cell death in breast cancer cells

Karakas, Didem; Akar, Remzi Okan; Gokmen, Zeliha; Ulukaya, Engin; Deniz, Nahide Gulsah (TR- Dizin, 2019)

Abstract: Breast cancer is the most-diagnosed cancer type among women. The triple-negative subtype is an especially aggressive type of breast cancer. Although chemotherapy is almost the only option for the treatment of ...
Synthesis and investigation of cytotoxicity of new N- and S,S-substituted-1,4-naphthoquinone (1,4-NQ) derivatives on selected cancer lines

Gokmen, Zeliha; Onan, Mehmet Erdi; Deniz, Nahide Gulsah; Karakas Zeybek, Didem; Ulukaya, Engin (Taylor & Francis Inc, 2019)

1,4-Naphthoquinones (1,4-NQ) have been reported to possess a variety of pharma-cological properties including antibacterial, antifungal, antiviral, anti-inflammatory, anti-artherosclerotic, and anticancer effects. In this ...