Browsing by Author "Gurel-Gurevin, Ebru"

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Chloroquine used in combination with chemotherapy synergistically suppresses growth and angiogenesis in vitro and in vivo

Gurel-Gurevin, Ebru; Kiyan, Hulya Tuba; Esener, Osman Behzat Burak; Aydinlik, Seyma; Uvez, Ayca; Ulukaya, Engin; Dimas, Konstantinos; Armutak, Elif Ilkay (Int Inst Anticancer Research, 2018)

Background: The inhibition of autophagy using pharmacological inhibitors such as chloroquine may be an effective strategy to overcome chemotherapy or resistance to anti-angiogenic therapy. Materials and Methods: The cytotoxic ...
Palladium (II) complex and thalidomide intercept angiogenic signaling via targeting FAK/Src and Erk/Akt/PLC gamma dependent autophagy pathways in human umbilical vein endothelial cells

Aydinlik, Seyma; Uvez, Ayca; Kiyan, Hulya Tuba; Gurel-Gurevin, Ebru; Yilmaz, Veysel Turan; Ulukaya, Engin (Elsevier, 2021)

The current study assessed the effects of the thalidomide and palladium (II) saccharinate complex of terpyridine on the suppression of angiogenesis-mediated cell proliferation. The viability was assessed after treatment ...