Browsing by Author "Hancer, Veysel Sabri"
Now showing items 1-15 of 15
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Aberrant activation-induced cytidine deaminase gene expression links BCR/ABL1-negative classical myeloproliferative neoplasms
Dermenci, Hasan; Daglar Aday, Aynur; Akadam Teker, Aysegul Basak; Hancer, Veysel; Gelmez, Metin Yusuf; Nalcaci, Meliha; Yavuz, Akif Selim (TR- Dizin, 2022)Aim: Activation-induced cytidine deaminase (AID) has been associated with tumor initiation and development because of its ability to generate DNA damage and somatic mutations that cause genomic instability. This study ... -
A case mimicking chronic myeloid leukemia with t(8;22)(p11;q11)/BCR-FGFR1 and sequential transformation to B-acute lymphoblastic leukemia and acute myeloid leukemia
Bayrak, Ayse Gul; Ucur, Ali; Daglar-Aday, Aynur; Bagatır, Gulcin; Erdem, Simge; Hancer, Veysel Sabri; Nalcacı, Meliha; Ozturk, Sukru; Cefle, Kivanc; Palanduz, Sukru; Yavuz, Akif Selim (Springer Science and Business Media Deutschland GmbH, 2021)Myeloid/lymphoid neoplasm is a rare malignancy with an aggressive course and rapid transformation to acute myeloid leukemia (AML), or less frequently to acute lymphoblastic leukemia (ALL). Cases with t(8;22)(p11;q11) ... -
Case report of a young patient with transthyretin amyloidosis associated with Gly67Ala mutation
Salihoglu, Ayse; Yildirim, Suleyman; Ar, Muhlis Cem; Hancer, Veysel Sabri; Bozcan, Selma; Yilmaz, Umut; Serin, Nergis; Tuzuner, Nukhet; Celik, Aykut Ferhat (Taylor & Francis Ltd, 2019)Hereditary transthyretin-mediated amyloidosis (hATTR) is a rare, systemic and progressive autosomal dominant disease caused by mutations in the TTR gene. Systemic deposition of amyloidogenic mutant transthyretin results ... -
Cholangitis, döhle bodies, may-hegglin anomaly
Cholangitis, Döhle bodies, May-Hegglin anomaly -
The clinical significance of jak2v617f mutation for philadelphia-negative chronic myeloproliferative neoplasms in patients with splanchic vein thrombosis
Hindilerden, Fehmi; Hindilerden, Ipek Yonal; Pinarbasi Simsek, Binnur; Hancer, Veysel Sabri; Kaymakoglu, Sabahattin; Kucukkaya, Reyhan Diz; Nalcaci, Meliha (Cig Media Group, Lp, 2019)Context: High prevalence of JAK2V617F mutation in splanchic vein thrombosis (SVT), including Budd-Chiari syndrome (BCS) and portal vein thrombosis (PVT) raised suspicion of an underlying Philadelphiaenegative chronic ... -
Kruppel-Like transcription factor-4 gene expression and DNA methylation status in type 2 diabetes and diabetic nephropathy patients
Coskun, Zeynep Mine; Ersoz, Melike; Adas, Mine; Hancer, Veysel Sabri; Boysan, Serife Nur; Gonen, Mustafa Sait; Acar, Aynur (Elsevier Science Inc, 2019)Background/Aim. Diabetic nephropathy (DN) is one of the most serious microvascular complications in diabetic patients. The kruppel-like transcription factor-4 (KLF-4) affects the expression of genes involved in the ... -
New indicator of cellular ischemia in coronary slow-flow phenomenon: cell-free DNA
Yolcu, M.; Dogan, A.; Kurtoglu, N.; Hancer, V.S.; Gürbüzel, M (Turkish Society of Cardiology, 2020)Objective: Coronary slow-flow phenomenon (CSFP) is defined as the delayed arrival of coronary blood flow to the distal vascular bed in at least 1 major epicardial coronary artery. Cell-free DNA (cfDNA) is a type of DNA ... -
A novel COL3A1c.2644G > T; p.(Gly882Cys) variant in a Turkish family with vascular ehlers-danlos syndrome
Aydiner, Omer; Hancer, Veysel Sabri (Karger, 2020)Vascular Ehlers-Danlos syndrome (vEDS) is an autosomal dominant disease, also known as EDS type IV. The estimated prevalence for all EDS varies between 1/10,000 and 1/25,000 with EDS type IV representing approximately 5-10% ... -
A novel pathological arsb mutation (c.870G>A; p.Trp290stop) in mucopolysaccharidosis type VI patients
Hancer, Veysel Sabri; Buyukdogan, Murat; Babameto-Laku, Anila (Karger, 2019)Mucopolysaccharidosis (MPS) type VI, also known as Maroteaux-Lamy syndrome, is a lysosomal storage disorder, characterized by the deficiency of the arylsulfatase B enzyme. The clinical phenotype and severity of the illness ... -
Pharmacogenetic aspect of intravitreal ranibizumab treatment in neovascular age-related macular degeneration: a five-year follow-up
Şengül, Elvan Alper; Artunay, Ozgur; Rasier, Rifat; Kockar, Alev; Afacan, Ceyda; Hancer, Veysel Sabri; Yuzbasioglu, Erdal (Taylor & Francis Inc, 2018)Purpose: This study aims to evaluate the role of complement factor H (CFH) in response to intravitreal ranibizumab (IVR) treatment, which is administered to patients with neovascular age-related macular degeneration ... -
Prognostic significance of carbonic anhydrase IX overexpression in stage III non-small cell lung cancer patients after neoadjuvant treatment
Ibis, Kamuran; Saglam, Sezer; Saglam, Esra Kaytan; Firat, Pinar; Yilmazbayhan, Dilek; Toker, Alper; Ozkan, Berker; Hancer, Veysel Sabri; Buyukdogan, Murat; Disci, Rian; Pilanci, Kezban Nur (Elsevier Gmbh, Urban & Fischer Verlag, 2018)Background: To assess the prognostic importance of carbonic anhydrase IX (CA IX), a hypoxic biomarker, after neoadjuvant treatment in Stage III non-small cell lung cancer (NSCLC) patients. Methods: Tissue CA IX expression ... -
The relationship between clinical parameters and hepatocyte growth factor/c-Met levels in the sperm of infertile males
Kayan, Basak Ozge; Hancer, Veysel Sabri; Gormus, Uzay; Ozcan, Cenk; Abike, Faruk; Baykal, Cem Murat (IMR PRESS, 2022)Objective: Hepatocyte growth factor is a pleiotropic cytokine with potent mitogenic activity in many organs and tissues. The receptor for hepatocyte growth factor is c-Met, a transmembrane glycoprotein with tyrosine kinase ... -
Three factor 11 mutations associated with factor XI deficiency in a Turkish family
Hancer, Veysel Sabri; Gokgoz, Zafer; Buyukdogan, Murat (Galenos Yayincilik, 2018)Factor XI (FXI) is a homodimeric serine protease, which is produced in the liver and circulates in the plasma complexed with high-molecular-weight kininogen. FXI plays an important role in the amplification of the initial ... -
Three novel calreticulin mutations in two Turkish patients
Hancer, Veysel Sabri; Tokgoz, Huseyin; Guvenc, Serkan; Caliskan, Umran; Buyukdogan, Murat (Galenos Yayincilik, 2017)Calreticulin (CALR) mutations were first identified exclusively in JAK2-MPL-negative essential thrombocythemia (ET) and primary myelofibrosis (PMF) at a rate of 60%-88%, accounting for 1/4 to 1/3 of all patients with ... -
Two rare pathogenic HBB variants in a patient with beta-thalassemia intermedia
Hancer, Veysel Sabri; Fisgin, Tunc; Buyukdogan, Murat (Galenos Yayincilik, 2020)The β-thalassemias are a group of hereditary disorders with autosomal recessive inheritance characterized by the presence of defective synthesis of the β-globin chain, an integral component of the hemoglobin molecule, ...
