Browsing by Author "Koyuncu Irmak, Duygu"
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Combination therapy using nanomaterials and stem cells to treat spinal cord injuries
Zarepour, Arezou; Bal Öztürk, Ayça; Koyuncu Irmak, Duygu; Yaşayan, Gökçen; Gökmen, Aylin; Karaöz, Erdal; Zarepour, Atefeh; Zarrabi, Ali; Mostafavi, Ebrahim (Elsevier Science, 2022)As a part of the central nervous system, the spinal cord (SC) provides most of the communications between the brain and other parts of the body. Any damage to SC interrupts this communication, leading to serious ... -
Generation of induced pluripotent stem cells from human bone marrow-derived mesenchymal stem cells
Koyuncu Irmak, Duygu; Karaöz, Erdal (Springer Link, 2021)Adult somatic cells can be reprogrammed and become pluripotent called induced pluripotent stem cells (iPSC) when they are induced by the stemness genes. The iPSCs have been representing a research and development platform ... -
Mesenchymal stem cells for the treatment of covid-19: why and when they should be used?
Darıcı, Hakan; Sun, Eda; Irmak, Duygu Koyuncu; Karaöz, Erdal (Nova Science Publishers, 2020)COVID-19 is a pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which caused deaths of more than 300.000 people around the world within the first few months of 2020. SARS-CoV-2 uses ACE2 ... -
Mesenchymal stem cells for the treatment of covid-19: why and when they should be used?
Darıcı, Hakan; Sun, Eda; Koyuncu Irmak, Duygu; Karaöz, Erdal (Nova Science Publishers, 2021)COVID-19 is a pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which caused deaths of more than 300.000 people around the world within the first few months of 2020. SARS-CoV-2 uses ACE2 ... -
Performing the comparative analysis to understand the functional roles of genes in different pathways of cardiomyopathy disease
Atak, Evren; Karaoğlu, Dilara; Serttürk, Seda; Koyuncu Irmak, Duygu; Yenenler-Kutlu, Aslı (Elsevier, 2021)Personalized medicine is one of the popular approaches in biological sciences. Due to the great attention in personalized medicine, there exists a need for health decision algorithms developed through high-level ... -
Safety and efficacy of the stem cell transplantation in friedreich's ataxia: a report of three cases
Azeri, Rıza; Irmak, Duygu Koyuncu; Sun, Eda; Karaöz, Erdal (IJPHY PUBLISHERS, 2021)Background: Friedreich's ataxia is a progressive degenerative disorder caused by deficiency of the frataxin protein. Expanded GAA repeats in intron 1 of the FXN gene lead to its heterochromatinization and transcriptional ... -
Stem cell based therapy option in COVID-19: is it really promising?
Koyuncu Irmak, Duygu; Darıcı, Hakan; Karaöz, Erdal (INT SOC AGING & DISEASE, 2020)The COVID-19 patients were first detected in China, in December 2019, then the novel virus with associated pneumonia and other diseases spread quickly to worldwide becoming a serious public health intimidation. Despite all ... -
The systematic effect of mesenchymal stem cell therapy in critical COVID-19 patients: a prospective double controlled trial
Adas, G.; Cukurova, Z.; Kart Yasar, K.; Yilmaz, R.; Isiksacan, N.; Kasapoglu, P.; Yesilbag, Z.; Koyuncu, I. D.; Karaoz, E. (Sage Journals, 2021)The aim of this clinical trial was to control the cytokine storm by administering mesenchymal stem cells (MSCs) to critically-ill COVID-19 patients, to evaluate the healing effect, and to systematically investigate how the ...
