Browsing by Author "Kucukcankurt, Fulya"

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Prognostic evidence of LEF1 isoforms in childhood acute lymphoblastic leukemia

Erbilgin, Yucel; Hatirnaz Ng, Ozden; Can, Ismail; Firtina, Sinem; Kucukcankurt, Fulya; Karaman, Serap (WILEY, 2021)

Introduction: The lymphoid enhancer factor 1 (LEF1) is a DNA-binding transcription factor that functions in the Wnt signaling pathway. Increased LEF1 activity is associated with progression of several types of cancer ...
PTEN and AKT1 variations in childhood T-Cell acute lymphoblastic leukemia

Kucukcankurt, Fulya; Erbilgin, Yucel; Firtina, Sinem; Ng, Ozden Hatirnaz; Karakas, Zeynep; Celkan, Tiraje; Unuvar, Aysegul; Ozbek, Ugur; Sayitoglu, Muge (Galenos Yayincilik, 2020)

Objective: PTEN/AKT pathway deregulations have been reported to be associated with treatment response in acute leukemia. This study examined pediatric T-cell acute lymphoblastic leukemia (T-ALL) samples for PTEN and AKT1 ...
Zinc finger protein 384 ( ZNF384) impact on childhood mixed phenotype acute leukemia and B-cell precursor acute lymphoblastic leukemia

Sudutan, Tugce; Erbilgin, Yucel; Hatırnaz, Ozden; Karaman, Serap; Karakas, Zeynep; Kucukcankurt, Fulya; Celkan, Tiraje; Timur, Cetin; Ozdemir, Gul Nihal; Hacısalihoglu, Sadan; Aylan Gelen, Sema; Sayitoglu, Muge (Taylor and Francis, 2022)

B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is a heterogeneous malignancy and consists of several genetic abnormalities. Some of these abnormalities are used in clinics for risk calculation and treatment ...