Browsing by Author "Kuo, Ching-Ying"
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Protoflavone-chalcone hybrids exhibit enhanced antitumor action through modulating redox balance, depolarizing the mitochondrial membrane, and inhibiting ATR-dependent signaling Latif, Ahmed Dhahir; Jernei, Tamas; Podolski-Renic, Ana; Kuo, Ching-Ying; Vagvolgyi, Mate; Girst, Gabor; Zupko, Istvan; Develi, Elif Sedef; Ulukaya, Engin; Wang, Hui-Chun; Pesic, Milica; Csampai, Antal; Hunyadi, Attila (Mdpi, 2020)Hybrid compounds combine fragments with complementary targets to achieve a common pharmacological goal. This approach represents an increasingly popular strategy for drug discovery. In this work, we aimed to design antitumor ...