Browsing by Author "Oztel, Olga Nehir"
Now showing items 1-5 of 5
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Determination of antibiotic impurities in good manufacturing practices-grade cell therapy medicinal products
Oztel, Olga Nehir; Korkmaz, Seval; Karaoz, Erdal (Taylor & Francis Inc, 2020)Backrounds: According to the regulations of the health autorities, cell-based therapy products must be manufactured in good manufacturing production (GMP) facilities, fulfilling the required GMP standards. Products developed ... -
Efficacy of stem cell therapy in ambulatory and nonambulatory children with Duchenne muscular dystrophy - Phase I-II
Dai, Alper; Baspinar, Osman; Yesilyurt, Ahmet; Sun Gungorurler, Eda; Aydemir, Cigdem Inci; Oztel, Olga Nehir; Karaoz, Erdal (Dove Medical Press Ltd, 2018)Purpose: Duchenne muscular dystrophy (DMD) is an X-linked recessive pediatric disorder that ultimately leads to progressive muscle degeneration. It has been known that cell-based therapies were used to promote muscle ... -
Isolation, culture, cryopreservation, and preparation of skin-derived fibroblasts as a final cellular product under good manufacturing practice-compliant conditions
Cell-based therapies have become a popular approach in the field of regenerative medicine. Human fibroblast cells, one of the cell types widely used in clinical applications, have been used for skin regeneration and wound ... -
Isolation, culture, cryopreservation, and preparation of umbilical cord-derived mesenchymal stem cells as a final cellular product under good manufacturing practices-compliant conditions
Mesenchymal stem cells have gained popularity in cell-based therapies due to their regenerative capabilities, immunomodulation properties, and paracrine activity through trophic factors. It is of utmost importance to ... -
Validation of the media fill method for solid tissue processing in good manufacturing practice-compliant cell production
Over the past few years, a large number of clinical studies for advanced therapy medicinal products have been registered and/or conducted for treating various diseases around the world and many have generated very exciting ...
