Browsing by Author "Sayitoğlu, Müge"
Now showing items 1-6 of 6
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Activation-Induced cytidine deaminase (AID) and uracil N-glycosylase (UNG) novel homozygous gene variants in adult hyper-IgM syndrome
Activation-Induced Cytidine Deaminase (AID) and Uracil N-glycosylase (UNG) novel homozygous gene variants in adult hyper-IgM syndrome -
Dasatinib-related pleural effusion and lymphocytosis rates are different between adult and pediatric patients with Philadelphia chromosome-positive leukemias: are age and comorbidities only to blame?
Kılıçarslan, Necati Alp; Börekçi, Şermin; Özdemir, Gül Nihal; Sayitoğlu, Müge; Eskazan, Ahmet Emre (Taylor and Francis, 2022)No Abstract Available -
A novel foxn1 variant is identified in two siblings with nude severe combined immunodeficiency
Fırtına, Sinem; Erol Cipe, Funda; Ng, Yuk Yin; Kiykim, Ayça; Ng, Özden Hatırnaz; Sudutan, Tuğce; Aydoğmuş, Çiğdem; Barış, Safa; Öztürk, Gülyüz; Aydıner, Elif; Özen, Ahmet; Sayitoğlu, Müge (Springer/Plenum Publishers, 2019)Severe combined immunodeficiency (SCID) is the most severe form of primary immunodeficiencies (PIDs) caused by gene variants that lead to a failure of functional T cell development, with or without accompanying defects ... -
Prognostic gene alterations and clonal changes in childhood B-ALL
Erbilgin, Yücel; Fırtına, Sinem; Mercan, Sevcan; Ng, Özden Hatırnaz; Karaman, Serap; Taşar, Orçun; Karakaş Zeybek, Didem; Celkan, Tulin Tiraje; Zengin, Emine; Sarper, Nazan; Yildirmak, Zeynep Yildiz; Şişko, Sinem; Özbek, Uğur; Sayitoğlu, Müge (Pergamon-Elsevier Science Ltd, 2019)Genomic profiles of leukemia patients lead to characterization of variations that provide the molecular classification of risk groups, prediction of clinical outcome and therapeutic decisions. In this study, we examined ... -
Tanısı zor tek gen hastalıklarında hedefe yönelik yeni nesil dizileme panel tasarımı: primer immün yetersizlik örneği
Fırtına, Sinem; Hatırnaz Ng, Özden; Sayitoğlu, Müge; Yin Ng, Yuk (DergiPark, 2020)Amaç: Yeni nesil dizileme teknolojileri bugün çok sayıda aday genin, genomun tüm kodlayan bölgelerinin hatta tüm genomun analizini tek seferde ve kısa süre içerisinde düşük maliyet ve yüksek hassasiyette, güvenilir bir ... -
Zinc finger protein 384 ( ZNF384) impact on childhood mixed phenotype acute leukemia and B-cell precursor acute lymphoblastic leukemia
Sudutan, Tuğce; Erbilgin, Yücel; Hatırnaz, Özden; Karaman, Serap; Karakaş, Zeynep; Küçükcankurt, Fulya; Celkan, Tülin Tiraje; Timur, Çetin; Özdemir, Gül Nihal; Hacısalihoglu, Sadan; Aylan Gelen, Sema; Sayitoğlu, Müge (Taylor and Francis, 2022)B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is a heterogeneous malignancy and consists of several genetic abnormalities. Some of these abnormalities are used in clinics for risk calculation and treatment ...
