Browsing by Author "Sethi, Gautam"
Now showing items 1-5 of 5
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Long noncoding RNAs (lncRNAs) in pancreatic cancer progression
Ashrafizadeh, Milad; Rabiee, Navid; Prem Kumar, Alan; Sethi, Gautam; Zarrabi, Ali; Wang, Yuzhuo (Elsevier Science, 2022)Long noncoding RNAs (lncRNAs) are RNA molecules involved in gene regulation at transcriptional, post-transcriptional, and epigenetic levels. lncRNAs participate in regulating apoptosis and autophagy in pancreatic cancer ... -
NF-κB as a regulator of cancer metastasis and therapy response: A focus on epithelial-mesenchymal transition
Mirzaei , Sepideh; Saghari, Sam; Bassiri, Farzaneh; Raesi, Rasoul; Zarrabi, Ali; Hushmandi, Kiavash; Sethi, Gautam; Tergaonkar, Vinay (Wiley, 2022)Metastasis of tumor cells is a complex challenge and significantly diminishes theoverall survival and prognosis of cancer patients. The epithelial‐to‐mesenchymaltransition (EMT) is a well‐known mechanism responsible for ... -
Non-coding RNA-based regulation of inflammation
Ashrafizadeh, Milad; Zarrabi, Ali; Mostafavi, Ebrahim; Aref, Amir Reza; Sethi, Gautam; Wang, Lingzhi; Tergaonkar, Vinay (Elsevier Science, 2022)nflammation is a multifactorial process and various biological mechanisms and pathways participate in its development. The presence of inflammation is involved in pathogenesis of different diseases such as diabetes mellitus, ... -
Non-coding RNAs and macrophage interaction in tumor progression
Entezari, Maliheh; Sadrkhanloo, Mehrdokht; Rashidi, Mohsen; Asnaf, Sholeh Etehad; Taheriazam, Afshin; Hashemi, Mehrdad; Ashrafizadeh, Milad; Zarrabi, Ali; Rabiee, Navid; Hushmandi, Kiavash; Mirzaei, Sepideh; Sethi, Gautam (Elsevier Ireland Ltd, 2022)The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage polarization in TME to affect cancer progression. ... -
Wnt/β-Catenin signaling as a driver of hepatocellular carcinoma progression: an emphasis on molecular pathways
Deldar Abad Paskeh, Mahshid; Mirzaei, Sepideh; Ashrafizadeh, Milad; Zarrabi, Ali; Sethi, Gautam (Dove Medical Press, 2021)Liver cancers cause a high rate of death worldwide and hepatocellular carcinoma (HCC) is considered as the most common primary liver cancer. HCC remains a challenging disease to treat. Wnt/β-catenin signaling pathway is ...
